ASKשאלו

BODY BEFORE THOUGHT · EVIDENCE & PUBLICATIONS

Every claim stays attached to its source, boundary and status.

This map unifies both canonical editions without promoting hypotheses into findings or inventing bibliographic details that the lectures did not supply.

EPISTEMIC GRAMMAR

CLAIM → SOURCE → EVIDENCE LEVEL → LIMITATIONS → COUNTEREVIDENCE

  1. 01Empirical result
  2. 02Supported interpretation
  3. 03Flow Hijacked synthesis
  4. 04Formal transfer
  5. 05New hypothesis
  6. 06Open question

Publication titles and author strings remain in the source language. The two bibliographies aligned to 100 items; deduplication used DOI, PMID, canonical title and author/year wherever those fields were available.

48 MAPPED CLAIMS

A responsibility map for each claim—not a wall of citations.

C01

SUPPORTED INTERPRETATION · conditional_evidence · LECTURE PAGE 6

The first conscious sentence is often not the first event in the system.

What the map supports

The first conscious sentence is often not the first event in the system.

Return to the public explanation

Inference boundary

Temporal precedence does not prove that bodily change causes a later thought. Reciprocal causation and common causes remain possible.

Status and counterevidence

conditional_evidenceR01-R05, R10, R14-R18

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

11 linked sources — open details
R01SUPPORTED INTERPRETATION

Interoception and Mental Health: A Roadmap

Khalsa SS et al

Claim boundary: Temporal precedence does not prove that bodily change causes a later thought. Reciprocal causation and common causes remain possible.

Publication record
R02SUPPORTED INTERPRETATION

The Emerging Science of Interoception: Sensing, Integrating, Interpreting, and Regulating Signals within the Self

Chen WG et al

Claim boundary: Temporal precedence does not prove that bodily change causes a later thought. Reciprocal causation and common causes remain possible.

Publication record
R03SUPPORTED INTERPRETATION

How do you feel? Interoception: the sense of the physiological condition of the body

Craig AD

Claim boundary: Temporal precedence does not prove that bodily change causes a later thought. Reciprocal causation and common causes remain possible.

Publication record
R04SUPPORTED INTERPRETATION

Neural systems supporting interoceptive awareness

Critchley HD, Wiens S, Rotshtein P, Ohman A, Dolan RJ

Claim boundary: Temporal precedence does not prove that bodily change causes a later thought. Reciprocal causation and common causes remain possible.

Publication record
R05SUPPORTED INTERPRETATION

Interoception and emotion

Critchley HD, Garfinkel SN

Claim boundary: Temporal precedence does not prove that bodily change causes a later thought. Reciprocal causation and common causes remain possible.

Publication record
R10SUPPORTED INTERPRETATION

Brain-body physiology: local, reflex, and central communication

Sammons M et al

Claim boundary: Temporal precedence does not prove that bodily change causes a later thought. Reciprocal causation and common causes remain possible.

Publication record
R14SUPPORTED INTERPRETATION

Physiological feelings

Pace-Schott EF et al

Claim boundary: Temporal precedence does not prove that bodily change causes a later thought. Reciprocal causation and common causes remain possible.

Publication record
R15SUPPORTED INTERPRETATION

The functional role of cardiac activity in perception and action

Skora L, Livermore JJA, Roelofs K

Claim boundary: Temporal precedence does not prove that bodily change causes a later thought. Reciprocal causation and common causes remain possible.

Publication record
R16SUPPORTED INTERPRETATION

Brain-heart interactions: physiology and clinical implications

Silvani A et al

Claim boundary: Temporal precedence does not prove that bodily change causes a later thought. Reciprocal causation and common causes remain possible.

Publication record
R17SUPPORTED INTERPRETATION

Neural mechanisms of respiratory interoception

Chan PYS, Lee LY, Davenport PW

Claim boundary: Temporal precedence does not prove that bodily change causes a later thought. Reciprocal causation and common causes remain possible.

Publication record
R18SUPPORTED INTERPRETATION

Cardiogenic control of affective behavioural state

Hsueh B et al

Claim boundary: Temporal precedence does not prove that bodily change causes a later thought. Reciprocal causation and common causes remain possible.

Publication record
C02

SUPPORTED INTERPRETATION · conditional_evidence · LECTURE PAGE 7

A body is regulated not only for the present it has, but for the future it expects.

What the map supports

A body is regulated not only for the present it has, but for the future it expects.

Return to the public explanation

Inference boundary

Allostasis is a broad regulatory framework, not a claim that every bodily change is centrally predicted or consciously represented.

Status and counterevidence

conditional_evidenceR21-R25, R35, R40

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

7 linked sources — open details
R21SUPPORTED INTERPRETATION

Allostasis: a model of predictive regulation

Sterling P

Claim boundary: Allostasis is a broad regulatory framework, not a claim that every bodily change is centrally predicted or consciously represented.

Publication record
R22SUPPORTED INTERPRETATION

Stress and the individual: mechanisms leading to disease

McEwen BS, Stellar E

Claim boundary: Allostasis is a broad regulatory framework, not a claim that every bodily change is centrally predicted or consciously represented.

Publication record
R23SUPPORTED INTERPRETATION

Stress, adaptation, and disease: allostasis and allostatic load

McEwen BS

Claim boundary: Allostasis is a broad regulatory framework, not a claim that every bodily change is centrally predicted or consciously represented.

Publication record
R24SUPPORTED INTERPRETATION

Uncertainty and stress: why it causes diseases and how it is mastered by the brain

Peters A, McEwen BS, Friston K

Claim boundary: Allostasis is a broad regulatory framework, not a claim that every bodily change is centrally predicted or consciously represented.

Publication record
R25SUPPORTED INTERPRETATION

Active inference, homeostatic regulation and adaptive behavioural control

Pezzulo G, Rigoli F, Friston K

Claim boundary: Allostasis is a broad regulatory framework, not a claim that every bodily change is centrally predicted or consciously represented.

Publication record
R35SUPPORTED INTERPRETATION

Allostatic interoceptive overload across psychiatric and neurological conditions

Santamaria-Garcia H et al

Claim boundary: Allostasis is a broad regulatory framework, not a claim that every bodily change is centrally predicted or consciously represented.

Publication record
R40SUPPORTED INTERPRETATION

The energetic cost of allostasis and allostatic load

Bobba-Alves N, Juster RP, Picard M

Claim boundary: Allostasis is a broad regulatory framework, not a claim that every bodily change is centrally predicted or consciously represented.

Publication record
C03

FLOW HIJACKED SYNTHESIS · flow_hijacked_synthesis · LECTURE PAGE 8

The question is not only what state the person is in, but how many other states remain reachable.

What the map supports

The question is not only what state the person is in, but how many other states remain reachable.

Return to the public explanation

Inference boundary

The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Status and counterevidence

flow_hijacked_synthesisR29-R40, R41-R66

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

38 linked sources — open details
R29FLOW HIJACKED SYNTHESIS

Interoceptive inference: from computational neuroscience to clinic

Owens AP, Allen M, Ondobaka S, Friston K

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
R30FLOW HIJACKED SYNTHESIS

An Active Inference Approach to Interoceptive Psychopathology

Paulus MP, Feinstein JS, Khalsa SS

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
R31FLOW HIJACKED SYNTHESIS

Computational psychosomatics and computational psychiatry: toward a joint framework for differential diagnosis

Petzschner FH, Weber LAE, Gard T, Stephan KE

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
R32FLOW HIJACKED SYNTHESIS

Allostatic Self-efficacy: a metacognitive theory of dyshomeostasis-induced fatigue and depression

Stephan KE et al

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
R33FLOW HIJACKED SYNTHESIS

A Bayesian computational model reveals a failure to adapt interoceptive precision estimates across depression, anxiety, eating, and substance use disorders

Smith R et al

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
R34FLOW HIJACKED SYNTHESIS

Transdiagnostic failure to adapt interoceptive precision estimates across affective, substance use, and eating disorders: replication and extension

Lavalley CA et al

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
R35FLOW HIJACKED SYNTHESIS

Allostatic interoceptive overload across psychiatric and neurological conditions

Santamaria-Garcia H et al

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
R36FLOW HIJACKED SYNTHESIS

In the Body’s Eye: the computational anatomy of interoceptive inference

Allen M, Levy AR, Parr T, Friston K

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
R37FLOW HIJACKED SYNTHESIS

Interoception as modeling, allostasis as control

Sennesh E et al

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
R38FLOW HIJACKED SYNTHESIS

Allostasis as a core feature of hierarchical gradients in the human brain

Katsumi Y et al

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
R39FLOW HIJACKED SYNTHESIS

Intrinsic timescales and predictive allostatic interoception in brain health and disease

Ibanez A, Northoff G

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
R40FLOW HIJACKED SYNTHESIS

The energetic cost of allostasis and allostatic load

Bobba-Alves N, Juster RP, Picard M

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
R41FLOW HIJACKED SYNTHESIS

Atypical interoception as a common risk factor for psychopathology: a review

Brewer R, Murphy J, Bird G

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
R42FLOW HIJACKED SYNTHESIS

Common threads: altered interoceptive processes across affective and anxiety disorders

Saltafossi M, Heck D, Kluger DS, Varga S

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
R43FLOW HIJACKED SYNTHESIS

Interoception in anxiety, depression, and psychosis: a review

Jenkinson PM, Fotopoulou A, Ibanez A, Rossell SL

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
R44FLOW HIJACKED SYNTHESIS

Major depressive disorder is associated with impaired interoceptive accuracy: a systematic review

Eggart M et al

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
R45FLOW HIJACKED SYNTHESIS

Interoceptive Processing in Substance Use Disorders: from neuroanatomy to computational models and predictive coding

Paulus MP

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
R46FLOW HIJACKED SYNTHESIS

A Systematic Review of Interoception in Substance Use Disorders

Im JJ et al

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
R47FLOW HIJACKED SYNTHESIS

Gastrointestinal Interoception in Eating Disorders: Charting a New Path

Khalsa SS, Berner LA, Anderson LM

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
R48FLOW HIJACKED SYNTHESIS

Interoception and Obsessive-Compulsive Disorder: a review of current evidence and future directions

Bragdon LB et al

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
R49FLOW HIJACKED SYNTHESIS

Interoception abnormalities in schizophrenia: review and integration with Bayesian accounts of psychosis

Yao B, Thakkar KN

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
R50FLOW HIJACKED SYNTHESIS

A roadmap to understanding interoceptive awareness and post-traumatic stress disorder: a scoping review

Leech K, Stapleton P, Patching A

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
R51FLOW HIJACKED SYNTHESIS

The brain-body disconnect: a somatic sensory basis for trauma-related disorders

Kearney BE, Lanius RA

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
R52FLOW HIJACKED SYNTHESIS

How processing of internal and external sensory information shapes engagement with the world after trauma

Harricharan S, McKinnon MC, Lanius RA

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
R53FLOW HIJACKED SYNTHESIS

Perceptual insensitivity to the modulation of interoceptive signals in depression, anxiety, and substance use disorders

Smith R et al

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
R54FLOW HIJACKED SYNTHESIS

Cardiac interoception in patients accessing secondary mental health services: a transdiagnostic study

Critchley HD et al

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
R55FLOW HIJACKED SYNTHESIS

Insular dysfunction of interoception in major depressive disorder: a neuroimaging perspective

Hu L et al

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
R56FLOW HIJACKED SYNTHESIS

Insula-cerebellar functional connectivity associated with somatic symptoms in mood disorders

Hattori S et al

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
R57FLOW HIJACKED SYNTHESIS

Interoceptive ability is uncorrelated across respiratory and cardiac axes in a large-scale psychophysical study

Banellis L et al

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
R58FLOW HIJACKED SYNTHESIS

Functional neurological disorder: new subtypes and shared mechanisms

Hallett M et al

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
R59FLOW HIJACKED SYNTHESIS

Persistent physical symptoms: definition, genesis, and management

Lowe B et al

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
R60FLOW HIJACKED SYNTHESIS

Persistent Physical Symptoms as Perceptual Dysregulation: a neuropsychobehavioral model and clinical implications

Henningsen P et al

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
R61FLOW HIJACKED SYNTHESIS

Effect of Pain Reprocessing Therapy vs Placebo and Usual Care for Patients With Chronic Back Pain

Ashar YK et al

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
R62FLOW HIJACKED SYNTHESIS

Shape shifting pain: chronification of back pain shifts brain representation

Hashmi JA et al

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
R63FLOW HIJACKED SYNTHESIS

Reward deficiency and anti-reward in pain chronification

Borsook D et al

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
R64FLOW HIJACKED SYNTHESIS

Beyond the symptom: the biology of fatigue

Raizen DM et al

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
R65FLOW HIJACKED SYNTHESIS

Neurobiology of eating behavior, nutrition, and health

Stover PJ et al

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
R66FLOW HIJACKED SYNTHESIS

Heterogeneous appetite patterns in depression: computational modeling of nutritional interoception, reward processing, and decision-making

Uchida Y et al

Claim boundary: The Flow Hijacked synthesis is an integration across literatures; it is not a validated diagnostic model.

Publication record
C04

EMPIRICAL RESULT · established_research · LECTURE PAGE 10

Interoception is not a dashboard of feelings. It is a distributed control architecture with a conscious surface.

What the map supports

Interoception is not a dashboard of feelings. It is a distributed control architecture with a conscious surface.

Return to the public explanation

Inference boundary

The boundary of interoception remains debated; some classifications treat pain, temperature or proprioception differently.

Status and counterevidence

established_researchR01-R10, R14-R20

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

17 linked sources — open details
R01EMPIRICAL RESULT

Interoception and Mental Health: A Roadmap

Khalsa SS et al

Claim boundary: The boundary of interoception remains debated; some classifications treat pain, temperature or proprioception differently.

Publication record
R02EMPIRICAL RESULT

The Emerging Science of Interoception: Sensing, Integrating, Interpreting, and Regulating Signals within the Self

Chen WG et al

Claim boundary: The boundary of interoception remains debated; some classifications treat pain, temperature or proprioception differently.

Publication record
R03EMPIRICAL RESULT

How do you feel? Interoception: the sense of the physiological condition of the body

Craig AD

Claim boundary: The boundary of interoception remains debated; some classifications treat pain, temperature or proprioception differently.

Publication record
R04EMPIRICAL RESULT

Neural systems supporting interoceptive awareness

Critchley HD, Wiens S, Rotshtein P, Ohman A, Dolan RJ

Claim boundary: The boundary of interoception remains debated; some classifications treat pain, temperature or proprioception differently.

Publication record
R05EMPIRICAL RESULT

Interoception and emotion

Critchley HD, Garfinkel SN

Claim boundary: The boundary of interoception remains debated; some classifications treat pain, temperature or proprioception differently.

Publication record
R06EMPIRICAL RESULT

Knowing your own heart: distinguishing interoceptive accuracy from interoceptive awareness

Garfinkel SN et al

Claim boundary: The boundary of interoception remains debated; some classifications treat pain, temperature or proprioception differently.

Publication record
R07EMPIRICAL RESULT

Towards a comprehensive assessment of interoception in a multi-dimensional framework

Suksasilp C, Garfinkel SN

Claim boundary: The boundary of interoception remains debated; some classifications treat pain, temperature or proprioception differently.

Publication record
R08EMPIRICAL RESULT

The new measures of interoceptive accuracy: a systematic review and assessment

Desmedt O, Luminet O, Walentynowicz M, Corneille O

Claim boundary: The boundary of interoception remains debated; some classifications treat pain, temperature or proprioception differently.

Publication record
R09EMPIRICAL RESULT

The Coding Logic of Interoception

Wang R, Chang RB

Claim boundary: The boundary of interoception remains debated; some classifications treat pain, temperature or proprioception differently.

Publication record
R10EMPIRICAL RESULT

Brain-body physiology: local, reflex, and central communication

Sammons M et al

Claim boundary: The boundary of interoception remains debated; some classifications treat pain, temperature or proprioception differently.

Publication record
R14EMPIRICAL RESULT

Physiological feelings

Pace-Schott EF et al

Claim boundary: The boundary of interoception remains debated; some classifications treat pain, temperature or proprioception differently.

Publication record
R15EMPIRICAL RESULT

The functional role of cardiac activity in perception and action

Skora L, Livermore JJA, Roelofs K

Claim boundary: The boundary of interoception remains debated; some classifications treat pain, temperature or proprioception differently.

Publication record
R16EMPIRICAL RESULT

Brain-heart interactions: physiology and clinical implications

Silvani A et al

Claim boundary: The boundary of interoception remains debated; some classifications treat pain, temperature or proprioception differently.

Publication record
R17EMPIRICAL RESULT

Neural mechanisms of respiratory interoception

Chan PYS, Lee LY, Davenport PW

Claim boundary: The boundary of interoception remains debated; some classifications treat pain, temperature or proprioception differently.

Publication record
R18EMPIRICAL RESULT

Cardiogenic control of affective behavioural state

Hsueh B et al

Claim boundary: The boundary of interoception remains debated; some classifications treat pain, temperature or proprioception differently.

Publication record
R19EMPIRICAL RESULT

Fear balance is maintained by bodily feedback to the insular cortex in mice

Klein AS et al

Claim boundary: The boundary of interoception remains debated; some classifications treat pain, temperature or proprioception differently.

Publication record
R20EMPIRICAL RESULT

Neural origins of human sickness in interoceptive responses to inflammation

Harrison NA et al

Claim boundary: The boundary of interoception remains debated; some classifications treat pain, temperature or proprioception differently.

Publication record
C05

EMPIRICAL RESULT · established_research · LECTURE PAGE 11

Better interoception does not mean feeling more. It means using bodily information more appropriately for the context.

What the map supports

Better interoception does not mean feeling more. It means using bodily information more appropriately for the context.

Return to the public explanation

Inference boundary

No single laboratory task establishes a person’s global interoceptive ability, and self-report should not be treated as an objective physiological measure.

Status and counterevidence

established_researchR05-R08, R54, R97-R99

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

8 linked sources — open details
R05EMPIRICAL RESULT

Interoception and emotion

Critchley HD, Garfinkel SN

Claim boundary: No single laboratory task establishes a person’s global interoceptive ability, and self-report should not be treated as an objective physiological measure.

Publication record
R06EMPIRICAL RESULT

Knowing your own heart: distinguishing interoceptive accuracy from interoceptive awareness

Garfinkel SN et al

Claim boundary: No single laboratory task establishes a person’s global interoceptive ability, and self-report should not be treated as an objective physiological measure.

Publication record
R07EMPIRICAL RESULT

Towards a comprehensive assessment of interoception in a multi-dimensional framework

Suksasilp C, Garfinkel SN

Claim boundary: No single laboratory task establishes a person’s global interoceptive ability, and self-report should not be treated as an objective physiological measure.

Publication record
R08EMPIRICAL RESULT

The new measures of interoceptive accuracy: a systematic review and assessment

Desmedt O, Luminet O, Walentynowicz M, Corneille O

Claim boundary: No single laboratory task establishes a person’s global interoceptive ability, and self-report should not be treated as an objective physiological measure.

Publication record
R54EMPIRICAL RESULT

Cardiac interoception in patients accessing secondary mental health services: a transdiagnostic study

Critchley HD et al

Claim boundary: No single laboratory task establishes a person’s global interoceptive ability, and self-report should not be treated as an objective physiological measure.

Publication record
R97EMPIRICAL RESULT

From many to none: meditation and the plasticity of the predictive mind

Laukkonen RE, Slagter HA

Claim boundary: No single laboratory task establishes a person’s global interoceptive ability, and self-report should not be treated as an objective physiological measure.

Publication record
R98EMPIRICAL RESULT

Systematic review and meta-analysis of the relationship between heartbeat-evoked potential and interoception

Coll MP et al

Claim boundary: No single laboratory task establishes a person’s global interoceptive ability, and self-report should not be treated as an objective physiological measure.

Publication record
R99EMPIRICAL RESULT

The respiratory resistance sensitivity task: quantifying respiratory interoception and metacognition

Nikolova N et al

Claim boundary: No single laboratory task establishes a person’s global interoceptive ability, and self-report should not be treated as an objective physiological measure.

Publication record
C06

SUPPORTED INTERPRETATION · conditional_evidence · LECTURE PAGE 12

There is no single volume knob for the inner body.

What the map supports

There is no single volume knob for the inner body.

Return to the public explanation

Inference boundary

Evidence for cross-modal independence is growing but task reliability remains an active methodological problem.

Status and counterevidence

conditional_evidenceR07-R09, R57, R97-R100

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

8 linked sources — open details
R07SUPPORTED INTERPRETATION

Towards a comprehensive assessment of interoception in a multi-dimensional framework

Suksasilp C, Garfinkel SN

Claim boundary: Evidence for cross-modal independence is growing but task reliability remains an active methodological problem.

Publication record
R08SUPPORTED INTERPRETATION

The new measures of interoceptive accuracy: a systematic review and assessment

Desmedt O, Luminet O, Walentynowicz M, Corneille O

Claim boundary: Evidence for cross-modal independence is growing but task reliability remains an active methodological problem.

Publication record
R09SUPPORTED INTERPRETATION

The Coding Logic of Interoception

Wang R, Chang RB

Claim boundary: Evidence for cross-modal independence is growing but task reliability remains an active methodological problem.

Publication record
R57SUPPORTED INTERPRETATION

Interoceptive ability is uncorrelated across respiratory and cardiac axes in a large-scale psychophysical study

Banellis L et al

Claim boundary: Evidence for cross-modal independence is growing but task reliability remains an active methodological problem.

Publication record
R97SUPPORTED INTERPRETATION

From many to none: meditation and the plasticity of the predictive mind

Laukkonen RE, Slagter HA

Claim boundary: Evidence for cross-modal independence is growing but task reliability remains an active methodological problem.

Publication record
R98SUPPORTED INTERPRETATION

Systematic review and meta-analysis of the relationship between heartbeat-evoked potential and interoception

Coll MP et al

Claim boundary: Evidence for cross-modal independence is growing but task reliability remains an active methodological problem.

Publication record
R99SUPPORTED INTERPRETATION

The respiratory resistance sensitivity task: quantifying respiratory interoception and metacognition

Nikolova N et al

Claim boundary: Evidence for cross-modal independence is growing but task reliability remains an active methodological problem.

Publication record
R100SUPPORTED INTERPRETATION

The heart rate discrimination task: estimating accuracy and precision of interoceptive beliefs

Legrand N et al

Claim boundary: Evidence for cross-modal independence is growing but task reliability remains an active methodological problem.

Publication record
C07

EMPIRICAL RESULT · established_research · LECTURE PAGE 14

The vagus matters greatly. It does not explain the body by itself.

What the map supports

The vagus matters greatly. It does not explain the body by itself.

Return to the public explanation

Inference boundary

Vagal anatomy does not justify using vagal tone as a synonym for safety, regulation, resilience or social engagement.

Status and counterevidence

established_researchR09-R10, R81, R88-R90, R94

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

7 linked sources — open details
R09EMPIRICAL RESULT

The Coding Logic of Interoception

Wang R, Chang RB

Claim boundary: Vagal anatomy does not justify using vagal tone as a synonym for safety, regulation, resilience or social engagement.

Publication record
R10EMPIRICAL RESULT

Brain-body physiology: local, reflex, and central communication

Sammons M et al

Claim boundary: Vagal anatomy does not justify using vagal tone as a synonym for safety, regulation, resilience or social engagement.

Publication record
R81EMPIRICAL RESULT

Immunoception: the insular cortex perspective

Rolls A

Claim boundary: Vagal anatomy does not justify using vagal tone as a synonym for safety, regulation, resilience or social engagement.

Publication record
R88EMPIRICAL RESULT

Sensory spinal interoceptive pathways and energy balance regulation

Munzberg H, Berthoud HR, Neuhuber W

Claim boundary: Vagal anatomy does not justify using vagal tone as a synonym for safety, regulation, resilience or social engagement.

Publication record
R89EMPIRICAL RESULT

Hepatic interoception in health and disease

Berthoud HR et al

Claim boundary: Vagal anatomy does not justify using vagal tone as a synonym for safety, regulation, resilience or social engagement.

Publication record
R90EMPIRICAL RESULT

Psychological interventions for interoception in mental health disorders: a systematic review of randomized controlled trials

Heim N et al

Claim boundary: Vagal anatomy does not justify using vagal tone as a synonym for safety, regulation, resilience or social engagement.

Publication record
R94EMPIRICAL RESULT

Transcutaneous auricular vagus nerve stimulation modulates interoceptive prediction-error processing and allostatic regulation

Ventura-Bort C, Weymar M

Claim boundary: Vagal anatomy does not justify using vagal tone as a synonym for safety, regulation, resilience or social engagement.

Publication record
C08

EMPIRICAL RESULT · established_research · LECTURE PAGE 15

Interoception is implemented by circuits, not by a single inner-body module.

What the map supports

Interoception is implemented by circuits, not by a single inner-body module.

Return to the public explanation

Inference boundary

Regional activation is not a diagnostic fingerprint. Insula or cingulate involvement does not establish a unique psychological process.

Status and counterevidence

established_researchR10-R13, R17, R38

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

6 linked sources — open details
R10EMPIRICAL RESULT

Brain-body physiology: local, reflex, and central communication

Sammons M et al

Claim boundary: Regional activation is not a diagnostic fingerprint. Insula or cingulate involvement does not establish a unique psychological process.

Publication record
R11EMPIRICAL RESULT

The Organization of the Primate Insular Cortex

Evrard HC

Claim boundary: Regional activation is not a diagnostic fingerprint. Insula or cingulate involvement does not establish a unique psychological process.

Publication record
R12EMPIRICAL RESULT

Saliency, switching, attention and control: a network model of insula function

Menon V, Uddin LQ

Claim boundary: Regional activation is not a diagnostic fingerprint. Insula or cingulate involvement does not establish a unique psychological process.

Publication record
R13EMPIRICAL RESULT

Interoceptive rhythms in the brain

Engelen T, Solca M, Tallon-Baudry C

Claim boundary: Regional activation is not a diagnostic fingerprint. Insula or cingulate involvement does not establish a unique psychological process.

Publication record
R17EMPIRICAL RESULT

Neural mechanisms of respiratory interoception

Chan PYS, Lee LY, Davenport PW

Claim boundary: Regional activation is not a diagnostic fingerprint. Insula or cingulate involvement does not establish a unique psychological process.

Publication record
R38EMPIRICAL RESULT

Allostasis as a core feature of hierarchical gradients in the human brain

Katsumi Y et al

Claim boundary: Regional activation is not a diagnostic fingerprint. Insula or cingulate involvement does not establish a unique psychological process.

Publication record
C09

SUPPORTED INTERPRETATION · conditional_evidence · LECTURE PAGE 16

The body does not merely change the level of a state; its rhythms can change when transitions are easiest.

What the map supports

The body does not merely change the level of a state; its rhythms can change when transitions are easiest.

Return to the public explanation

Inference boundary

Cardiac, respiratory and gastric phase effects are real research domains, but effect sizes and generalizability vary across tasks.

Status and counterevidence

conditional_evidenceR13-R18, R97-R100

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

10 linked sources — open details
R13SUPPORTED INTERPRETATION

Interoceptive rhythms in the brain

Engelen T, Solca M, Tallon-Baudry C

Claim boundary: Cardiac, respiratory and gastric phase effects are real research domains, but effect sizes and generalizability vary across tasks.

Publication record
R14SUPPORTED INTERPRETATION

Physiological feelings

Pace-Schott EF et al

Claim boundary: Cardiac, respiratory and gastric phase effects are real research domains, but effect sizes and generalizability vary across tasks.

Publication record
R15SUPPORTED INTERPRETATION

The functional role of cardiac activity in perception and action

Skora L, Livermore JJA, Roelofs K

Claim boundary: Cardiac, respiratory and gastric phase effects are real research domains, but effect sizes and generalizability vary across tasks.

Publication record
R16SUPPORTED INTERPRETATION

Brain-heart interactions: physiology and clinical implications

Silvani A et al

Claim boundary: Cardiac, respiratory and gastric phase effects are real research domains, but effect sizes and generalizability vary across tasks.

Publication record
R17SUPPORTED INTERPRETATION

Neural mechanisms of respiratory interoception

Chan PYS, Lee LY, Davenport PW

Claim boundary: Cardiac, respiratory and gastric phase effects are real research domains, but effect sizes and generalizability vary across tasks.

Publication record
R18SUPPORTED INTERPRETATION

Cardiogenic control of affective behavioural state

Hsueh B et al

Claim boundary: Cardiac, respiratory and gastric phase effects are real research domains, but effect sizes and generalizability vary across tasks.

Publication record
R97SUPPORTED INTERPRETATION

From many to none: meditation and the plasticity of the predictive mind

Laukkonen RE, Slagter HA

Claim boundary: Cardiac, respiratory and gastric phase effects are real research domains, but effect sizes and generalizability vary across tasks.

Publication record
R98SUPPORTED INTERPRETATION

Systematic review and meta-analysis of the relationship between heartbeat-evoked potential and interoception

Coll MP et al

Claim boundary: Cardiac, respiratory and gastric phase effects are real research domains, but effect sizes and generalizability vary across tasks.

Publication record
R99SUPPORTED INTERPRETATION

The respiratory resistance sensitivity task: quantifying respiratory interoception and metacognition

Nikolova N et al

Claim boundary: Cardiac, respiratory and gastric phase effects are real research domains, but effect sizes and generalizability vary across tasks.

Publication record
R100SUPPORTED INTERPRETATION

The heart rate discrimination task: estimating accuracy and precision of interoceptive beliefs

Legrand N et al

Claim boundary: Cardiac, respiratory and gastric phase effects are real research domains, but effect sizes and generalizability vary across tasks.

Publication record
C10

SUPPORTED INTERPRETATION · conditional_evidence · LECTURE PAGE 18

What looks excessive in the present may be a prediction policy that once minimized a different kind of error.

What the map supports

What looks excessive in the present may be a prediction policy that once minimized a different kind of error.

Return to the public explanation

Inference boundary

Predictive regulation is a systems-level interpretation; not every anticipatory response requires a detailed cortical generative model.

Status and counterevidence

conditional_evidenceR21-R25, R35, R37-R40

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

10 linked sources — open details
R21SUPPORTED INTERPRETATION

Allostasis: a model of predictive regulation

Sterling P

Claim boundary: Predictive regulation is a systems-level interpretation; not every anticipatory response requires a detailed cortical generative model.

Publication record
R22SUPPORTED INTERPRETATION

Stress and the individual: mechanisms leading to disease

McEwen BS, Stellar E

Claim boundary: Predictive regulation is a systems-level interpretation; not every anticipatory response requires a detailed cortical generative model.

Publication record
R23SUPPORTED INTERPRETATION

Stress, adaptation, and disease: allostasis and allostatic load

McEwen BS

Claim boundary: Predictive regulation is a systems-level interpretation; not every anticipatory response requires a detailed cortical generative model.

Publication record
R24SUPPORTED INTERPRETATION

Uncertainty and stress: why it causes diseases and how it is mastered by the brain

Peters A, McEwen BS, Friston K

Claim boundary: Predictive regulation is a systems-level interpretation; not every anticipatory response requires a detailed cortical generative model.

Publication record
R25SUPPORTED INTERPRETATION

Active inference, homeostatic regulation and adaptive behavioural control

Pezzulo G, Rigoli F, Friston K

Claim boundary: Predictive regulation is a systems-level interpretation; not every anticipatory response requires a detailed cortical generative model.

Publication record
R35SUPPORTED INTERPRETATION

Allostatic interoceptive overload across psychiatric and neurological conditions

Santamaria-Garcia H et al

Claim boundary: Predictive regulation is a systems-level interpretation; not every anticipatory response requires a detailed cortical generative model.

Publication record
R37SUPPORTED INTERPRETATION

Interoception as modeling, allostasis as control

Sennesh E et al

Claim boundary: Predictive regulation is a systems-level interpretation; not every anticipatory response requires a detailed cortical generative model.

Publication record
R38SUPPORTED INTERPRETATION

Allostasis as a core feature of hierarchical gradients in the human brain

Katsumi Y et al

Claim boundary: Predictive regulation is a systems-level interpretation; not every anticipatory response requires a detailed cortical generative model.

Publication record
R39SUPPORTED INTERPRETATION

Intrinsic timescales and predictive allostatic interoception in brain health and disease

Ibanez A, Northoff G

Claim boundary: Predictive regulation is a systems-level interpretation; not every anticipatory response requires a detailed cortical generative model.

Publication record
R40SUPPORTED INTERPRETATION

The energetic cost of allostasis and allostatic load

Bobba-Alves N, Juster RP, Picard M

Claim boundary: Predictive regulation is a systems-level interpretation; not every anticipatory response requires a detailed cortical generative model.

Publication record
C11

EMPIRICAL RESULT · established_research · LECTURE PAGE 19

Cost and flexibility are related questions, not the same question.

What the map supports

Cost and flexibility are related questions, not the same question.

Return to the public explanation

Inference boundary

Allostatic-load indices vary across studies and should not be treated as a universal clinical score for an individual.

Status and counterevidence

established_researchR22-R24, R35, R40

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

5 linked sources — open details
R22EMPIRICAL RESULT

Stress and the individual: mechanisms leading to disease

McEwen BS, Stellar E

Claim boundary: Allostatic-load indices vary across studies and should not be treated as a universal clinical score for an individual.

Publication record
R23EMPIRICAL RESULT

Stress, adaptation, and disease: allostasis and allostatic load

McEwen BS

Claim boundary: Allostatic-load indices vary across studies and should not be treated as a universal clinical score for an individual.

Publication record
R24EMPIRICAL RESULT

Uncertainty and stress: why it causes diseases and how it is mastered by the brain

Peters A, McEwen BS, Friston K

Claim boundary: Allostatic-load indices vary across studies and should not be treated as a universal clinical score for an individual.

Publication record
R35EMPIRICAL RESULT

Allostatic interoceptive overload across psychiatric and neurological conditions

Santamaria-Garcia H et al

Claim boundary: Allostatic-load indices vary across studies and should not be treated as a universal clinical score for an individual.

Publication record
R40EMPIRICAL RESULT

The energetic cost of allostasis and allostatic load

Bobba-Alves N, Juster RP, Picard M

Claim boundary: Allostatic-load indices vary across studies and should not be treated as a universal clinical score for an individual.

Publication record
C12

FLOW HIJACKED SYNTHESIS · flow_hijacked_synthesis · LECTURE PAGE 20

Agency depends partly on what the system believes it can afford – and partly on what it can actually afford.

What the map supports

Agency depends partly on what the system believes it can afford – and partly on what it can actually afford.

Return to the public explanation

Inference boundary

The lecture does not infer individual energy metabolism from subjective fatigue, nor does it frame fatigue as a single computational error.

Status and counterevidence

flow_hijacked_synthesisR32, R40, R64-R66

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

5 linked sources — open details
R32FLOW HIJACKED SYNTHESIS

Allostatic Self-efficacy: a metacognitive theory of dyshomeostasis-induced fatigue and depression

Stephan KE et al

Claim boundary: The lecture does not infer individual energy metabolism from subjective fatigue, nor does it frame fatigue as a single computational error.

Publication record
R40FLOW HIJACKED SYNTHESIS

The energetic cost of allostasis and allostatic load

Bobba-Alves N, Juster RP, Picard M

Claim boundary: The lecture does not infer individual energy metabolism from subjective fatigue, nor does it frame fatigue as a single computational error.

Publication record
R64FLOW HIJACKED SYNTHESIS

Beyond the symptom: the biology of fatigue

Raizen DM et al

Claim boundary: The lecture does not infer individual energy metabolism from subjective fatigue, nor does it frame fatigue as a single computational error.

Publication record
R65FLOW HIJACKED SYNTHESIS

Neurobiology of eating behavior, nutrition, and health

Stover PJ et al

Claim boundary: The lecture does not infer individual energy metabolism from subjective fatigue, nor does it frame fatigue as a single computational error.

Publication record
R66FLOW HIJACKED SYNTHESIS

Heterogeneous appetite patterns in depression: computational modeling of nutritional interoception, reward processing, and decision-making

Uchida Y et al

Claim boundary: The lecture does not infer individual energy metabolism from subjective fatigue, nor does it frame fatigue as a single computational error.

Publication record
C13

FORMAL TRANSFER · flow_hijacked_synthesis · LECTURE PAGE 22

The body that is felt is neither pure physiology nor pure belief. It is physiology interpreted through an uncertain model.

What the map supports

The body that is felt is neither pure physiology nor pure belief. It is physiology interpreted through an uncertain model.

Return to the public explanation

Inference boundary

Generative models are explanatory abstractions. The brain is not assumed to store explicit probability tables corresponding to the equations.

Status and counterevidence

formal transfer with stated boundariesR25-R31, R36-R39

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

11 linked sources — open details
R25FORMAL TRANSFER

Active inference, homeostatic regulation and adaptive behavioural control

Pezzulo G, Rigoli F, Friston K

Claim boundary: Generative models are explanatory abstractions. The brain is not assumed to store explicit probability tables corresponding to the equations.

Publication record
R26FORMAL TRANSFER

Active interoceptive inference and the emotional brain

Seth AK, Friston KJ

Claim boundary: Generative models are explanatory abstractions. The brain is not assumed to store explicit probability tables corresponding to the equations.

Publication record
R27FORMAL TRANSFER

Interoceptive predictions in the brain

Barrett LF, Simmons WK

Claim boundary: Generative models are explanatory abstractions. The brain is not assumed to store explicit probability tables corresponding to the equations.

Publication record
R28FORMAL TRANSFER

The theory of constructed emotion: an active inference account of interoception and categorization

Barrett LF

Claim boundary: Generative models are explanatory abstractions. The brain is not assumed to store explicit probability tables corresponding to the equations.

Publication record
R29FORMAL TRANSFER

Interoceptive inference: from computational neuroscience to clinic

Owens AP, Allen M, Ondobaka S, Friston K

Claim boundary: Generative models are explanatory abstractions. The brain is not assumed to store explicit probability tables corresponding to the equations.

Publication record
R30FORMAL TRANSFER

An Active Inference Approach to Interoceptive Psychopathology

Paulus MP, Feinstein JS, Khalsa SS

Claim boundary: Generative models are explanatory abstractions. The brain is not assumed to store explicit probability tables corresponding to the equations.

Publication record
R31FORMAL TRANSFER

Computational psychosomatics and computational psychiatry: toward a joint framework for differential diagnosis

Petzschner FH, Weber LAE, Gard T, Stephan KE

Claim boundary: Generative models are explanatory abstractions. The brain is not assumed to store explicit probability tables corresponding to the equations.

Publication record
R36FORMAL TRANSFER

In the Body’s Eye: the computational anatomy of interoceptive inference

Allen M, Levy AR, Parr T, Friston K

Claim boundary: Generative models are explanatory abstractions. The brain is not assumed to store explicit probability tables corresponding to the equations.

Publication record
R37FORMAL TRANSFER

Interoception as modeling, allostasis as control

Sennesh E et al

Claim boundary: Generative models are explanatory abstractions. The brain is not assumed to store explicit probability tables corresponding to the equations.

Publication record
R38FORMAL TRANSFER

Allostasis as a core feature of hierarchical gradients in the human brain

Katsumi Y et al

Claim boundary: Generative models are explanatory abstractions. The brain is not assumed to store explicit probability tables corresponding to the equations.

Publication record
R39FORMAL TRANSFER

Intrinsic timescales and predictive allostatic interoception in brain health and disease

Ibanez A, Northoff G

Claim boundary: Generative models are explanatory abstractions. The brain is not assumed to store explicit probability tables corresponding to the equations.

Publication record
C14

FORMAL TRANSFER · flow_hijacked_synthesis · LECTURE PAGE 23

A prediction error changes the model only to the extent that the system believes the error deserves to be trusted.

What the map supports

A prediction error changes the model only to the extent that the system believes the error deserves to be trusted.

Return to the public explanation

Inference boundary

Precision is a formal parameter whose neurobiological implementation is distributed and task-dependent; it should not be equated with one neurotransmitter or one region.

Status and counterevidence

formal transfer with stated boundariesR26-R34, R36

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

10 linked sources — open details
R26FORMAL TRANSFER

Active interoceptive inference and the emotional brain

Seth AK, Friston KJ

Claim boundary: Precision is a formal parameter whose neurobiological implementation is distributed and task-dependent; it should not be equated with one neurotransmitter or one region.

Publication record
R27FORMAL TRANSFER

Interoceptive predictions in the brain

Barrett LF, Simmons WK

Claim boundary: Precision is a formal parameter whose neurobiological implementation is distributed and task-dependent; it should not be equated with one neurotransmitter or one region.

Publication record
R28FORMAL TRANSFER

The theory of constructed emotion: an active inference account of interoception and categorization

Barrett LF

Claim boundary: Precision is a formal parameter whose neurobiological implementation is distributed and task-dependent; it should not be equated with one neurotransmitter or one region.

Publication record
R29FORMAL TRANSFER

Interoceptive inference: from computational neuroscience to clinic

Owens AP, Allen M, Ondobaka S, Friston K

Claim boundary: Precision is a formal parameter whose neurobiological implementation is distributed and task-dependent; it should not be equated with one neurotransmitter or one region.

Publication record
R30FORMAL TRANSFER

An Active Inference Approach to Interoceptive Psychopathology

Paulus MP, Feinstein JS, Khalsa SS

Claim boundary: Precision is a formal parameter whose neurobiological implementation is distributed and task-dependent; it should not be equated with one neurotransmitter or one region.

Publication record
R31FORMAL TRANSFER

Computational psychosomatics and computational psychiatry: toward a joint framework for differential diagnosis

Petzschner FH, Weber LAE, Gard T, Stephan KE

Claim boundary: Precision is a formal parameter whose neurobiological implementation is distributed and task-dependent; it should not be equated with one neurotransmitter or one region.

Publication record
R32FORMAL TRANSFER

Allostatic Self-efficacy: a metacognitive theory of dyshomeostasis-induced fatigue and depression

Stephan KE et al

Claim boundary: Precision is a formal parameter whose neurobiological implementation is distributed and task-dependent; it should not be equated with one neurotransmitter or one region.

Publication record
R33FORMAL TRANSFER

A Bayesian computational model reveals a failure to adapt interoceptive precision estimates across depression, anxiety, eating, and substance use disorders

Smith R et al

Claim boundary: Precision is a formal parameter whose neurobiological implementation is distributed and task-dependent; it should not be equated with one neurotransmitter or one region.

Publication record
R34FORMAL TRANSFER

Transdiagnostic failure to adapt interoceptive precision estimates across affective, substance use, and eating disorders: replication and extension

Lavalley CA et al

Claim boundary: Precision is a formal parameter whose neurobiological implementation is distributed and task-dependent; it should not be equated with one neurotransmitter or one region.

Publication record
R36FORMAL TRANSFER

In the Body’s Eye: the computational anatomy of interoceptive inference

Allen M, Levy AR, Parr T, Friston K

Claim boundary: Precision is a formal parameter whose neurobiological implementation is distributed and task-dependent; it should not be equated with one neurotransmitter or one region.

Publication record
C15

SUPPORTED INTERPRETATION · conditional_evidence · LECTURE PAGE 24

A nervous system does not only predict the body. Through action, it helps build the body it will sense next.

What the map supports

A nervous system does not only predict the body. Through action, it helps build the body it will sense next.

Return to the public explanation

Inference boundary

Active inference is one computational framework among several. Similar behavioral loops can be modeled using reinforcement learning, control theory or associative learning.

Status and counterevidence

conditional_evidenceR25-R31, R37

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

8 linked sources — open details
R25SUPPORTED INTERPRETATION

Active inference, homeostatic regulation and adaptive behavioural control

Pezzulo G, Rigoli F, Friston K

Claim boundary: Active inference is one computational framework among several. Similar behavioral loops can be modeled using reinforcement learning, control theory or associative learning.

Publication record
R26SUPPORTED INTERPRETATION

Active interoceptive inference and the emotional brain

Seth AK, Friston KJ

Claim boundary: Active inference is one computational framework among several. Similar behavioral loops can be modeled using reinforcement learning, control theory or associative learning.

Publication record
R27SUPPORTED INTERPRETATION

Interoceptive predictions in the brain

Barrett LF, Simmons WK

Claim boundary: Active inference is one computational framework among several. Similar behavioral loops can be modeled using reinforcement learning, control theory or associative learning.

Publication record
R28SUPPORTED INTERPRETATION

The theory of constructed emotion: an active inference account of interoception and categorization

Barrett LF

Claim boundary: Active inference is one computational framework among several. Similar behavioral loops can be modeled using reinforcement learning, control theory or associative learning.

Publication record
R29SUPPORTED INTERPRETATION

Interoceptive inference: from computational neuroscience to clinic

Owens AP, Allen M, Ondobaka S, Friston K

Claim boundary: Active inference is one computational framework among several. Similar behavioral loops can be modeled using reinforcement learning, control theory or associative learning.

Publication record
R30SUPPORTED INTERPRETATION

An Active Inference Approach to Interoceptive Psychopathology

Paulus MP, Feinstein JS, Khalsa SS

Claim boundary: Active inference is one computational framework among several. Similar behavioral loops can be modeled using reinforcement learning, control theory or associative learning.

Publication record
R31SUPPORTED INTERPRETATION

Computational psychosomatics and computational psychiatry: toward a joint framework for differential diagnosis

Petzschner FH, Weber LAE, Gard T, Stephan KE

Claim boundary: Active inference is one computational framework among several. Similar behavioral loops can be modeled using reinforcement learning, control theory or associative learning.

Publication record
R37SUPPORTED INTERPRETATION

Interoception as modeling, allostasis as control

Sennesh E et al

Claim boundary: Active inference is one computational framework among several. Similar behavioral loops can be modeled using reinforcement learning, control theory or associative learning.

Publication record
C16

EMPIRICAL RESULT · established_research · LECTURE PAGE 26

The deeper failure may be not sensing too little or too much, but changing trust too slowly.

What the map supports

The deeper failure may be not sensing too little or too much, but changing trust too slowly.

Return to the public explanation

Inference boundary

The task-based precision parameter is not a general clinical biomarker and should not be generalized to every interoceptive channel.

Status and counterevidence

established_researchR33-R34, R53-R57

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

7 linked sources — open details
R33EMPIRICAL RESULT

A Bayesian computational model reveals a failure to adapt interoceptive precision estimates across depression, anxiety, eating, and substance use disorders

Smith R et al

Claim boundary: The task-based precision parameter is not a general clinical biomarker and should not be generalized to every interoceptive channel.

Publication record
R34EMPIRICAL RESULT

Transdiagnostic failure to adapt interoceptive precision estimates across affective, substance use, and eating disorders: replication and extension

Lavalley CA et al

Claim boundary: The task-based precision parameter is not a general clinical biomarker and should not be generalized to every interoceptive channel.

Publication record
R53EMPIRICAL RESULT

Perceptual insensitivity to the modulation of interoceptive signals in depression, anxiety, and substance use disorders

Smith R et al

Claim boundary: The task-based precision parameter is not a general clinical biomarker and should not be generalized to every interoceptive channel.

Publication record
R54EMPIRICAL RESULT

Cardiac interoception in patients accessing secondary mental health services: a transdiagnostic study

Critchley HD et al

Claim boundary: The task-based precision parameter is not a general clinical biomarker and should not be generalized to every interoceptive channel.

Publication record
R55EMPIRICAL RESULT

Insular dysfunction of interoception in major depressive disorder: a neuroimaging perspective

Hu L et al

Claim boundary: The task-based precision parameter is not a general clinical biomarker and should not be generalized to every interoceptive channel.

Publication record
R56EMPIRICAL RESULT

Insula-cerebellar functional connectivity associated with somatic symptoms in mood disorders

Hattori S et al

Claim boundary: The task-based precision parameter is not a general clinical biomarker and should not be generalized to every interoceptive channel.

Publication record
R57EMPIRICAL RESULT

Interoceptive ability is uncorrelated across respiratory and cardiac axes in a large-scale psychophysical study

Banellis L et al

Claim boundary: The task-based precision parameter is not a general clinical biomarker and should not be generalized to every interoceptive channel.

Publication record
C17

SUPPORTED INTERPRETATION · conditional_evidence · LECTURE PAGE 27

A person can be too certain about one bodily story and too uncertain about another at the same time.

What the map supports

A person can be too certain about one bodily story and too uncertain about another at the same time.

Return to the public explanation

Inference boundary

Clinical heterogeneity is substantial; the same symptom label can arise from different combinations of attention, precision, prior expectation and physiology.

Status and counterevidence

conditional_evidenceR41-R57

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

17 linked sources — open details
R41SUPPORTED INTERPRETATION

Atypical interoception as a common risk factor for psychopathology: a review

Brewer R, Murphy J, Bird G

Claim boundary: Clinical heterogeneity is substantial; the same symptom label can arise from different combinations of attention, precision, prior expectation and physiology.

Publication record
R42SUPPORTED INTERPRETATION

Common threads: altered interoceptive processes across affective and anxiety disorders

Saltafossi M, Heck D, Kluger DS, Varga S

Claim boundary: Clinical heterogeneity is substantial; the same symptom label can arise from different combinations of attention, precision, prior expectation and physiology.

Publication record
R43SUPPORTED INTERPRETATION

Interoception in anxiety, depression, and psychosis: a review

Jenkinson PM, Fotopoulou A, Ibanez A, Rossell SL

Claim boundary: Clinical heterogeneity is substantial; the same symptom label can arise from different combinations of attention, precision, prior expectation and physiology.

Publication record
R44SUPPORTED INTERPRETATION

Major depressive disorder is associated with impaired interoceptive accuracy: a systematic review

Eggart M et al

Claim boundary: Clinical heterogeneity is substantial; the same symptom label can arise from different combinations of attention, precision, prior expectation and physiology.

Publication record
R45SUPPORTED INTERPRETATION

Interoceptive Processing in Substance Use Disorders: from neuroanatomy to computational models and predictive coding

Paulus MP

Claim boundary: Clinical heterogeneity is substantial; the same symptom label can arise from different combinations of attention, precision, prior expectation and physiology.

Publication record
R46SUPPORTED INTERPRETATION

A Systematic Review of Interoception in Substance Use Disorders

Im JJ et al

Claim boundary: Clinical heterogeneity is substantial; the same symptom label can arise from different combinations of attention, precision, prior expectation and physiology.

Publication record
R47SUPPORTED INTERPRETATION

Gastrointestinal Interoception in Eating Disorders: Charting a New Path

Khalsa SS, Berner LA, Anderson LM

Claim boundary: Clinical heterogeneity is substantial; the same symptom label can arise from different combinations of attention, precision, prior expectation and physiology.

Publication record
R48SUPPORTED INTERPRETATION

Interoception and Obsessive-Compulsive Disorder: a review of current evidence and future directions

Bragdon LB et al

Claim boundary: Clinical heterogeneity is substantial; the same symptom label can arise from different combinations of attention, precision, prior expectation and physiology.

Publication record
R49SUPPORTED INTERPRETATION

Interoception abnormalities in schizophrenia: review and integration with Bayesian accounts of psychosis

Yao B, Thakkar KN

Claim boundary: Clinical heterogeneity is substantial; the same symptom label can arise from different combinations of attention, precision, prior expectation and physiology.

Publication record
R50SUPPORTED INTERPRETATION

A roadmap to understanding interoceptive awareness and post-traumatic stress disorder: a scoping review

Leech K, Stapleton P, Patching A

Claim boundary: Clinical heterogeneity is substantial; the same symptom label can arise from different combinations of attention, precision, prior expectation and physiology.

Publication record
R51SUPPORTED INTERPRETATION

The brain-body disconnect: a somatic sensory basis for trauma-related disorders

Kearney BE, Lanius RA

Claim boundary: Clinical heterogeneity is substantial; the same symptom label can arise from different combinations of attention, precision, prior expectation and physiology.

Publication record
R52SUPPORTED INTERPRETATION

How processing of internal and external sensory information shapes engagement with the world after trauma

Harricharan S, McKinnon MC, Lanius RA

Claim boundary: Clinical heterogeneity is substantial; the same symptom label can arise from different combinations of attention, precision, prior expectation and physiology.

Publication record
R53SUPPORTED INTERPRETATION

Perceptual insensitivity to the modulation of interoceptive signals in depression, anxiety, and substance use disorders

Smith R et al

Claim boundary: Clinical heterogeneity is substantial; the same symptom label can arise from different combinations of attention, precision, prior expectation and physiology.

Publication record
R54SUPPORTED INTERPRETATION

Cardiac interoception in patients accessing secondary mental health services: a transdiagnostic study

Critchley HD et al

Claim boundary: Clinical heterogeneity is substantial; the same symptom label can arise from different combinations of attention, precision, prior expectation and physiology.

Publication record
R55SUPPORTED INTERPRETATION

Insular dysfunction of interoception in major depressive disorder: a neuroimaging perspective

Hu L et al

Claim boundary: Clinical heterogeneity is substantial; the same symptom label can arise from different combinations of attention, precision, prior expectation and physiology.

Publication record
R56SUPPORTED INTERPRETATION

Insula-cerebellar functional connectivity associated with somatic symptoms in mood disorders

Hattori S et al

Claim boundary: Clinical heterogeneity is substantial; the same symptom label can arise from different combinations of attention, precision, prior expectation and physiology.

Publication record
R57SUPPORTED INTERPRETATION

Interoceptive ability is uncorrelated across respiratory and cardiac axes in a large-scale psychophysical study

Banellis L et al

Claim boundary: Clinical heterogeneity is substantial; the same symptom label can arise from different combinations of attention, precision, prior expectation and physiology.

Publication record
C18

EMERGING EVIDENCE · experimental_evidence · LECTURE PAGE 28

The therapeutic target may be the ability to reweight evidence, not the ability to feel every signal more strongly.

What the map supports

The therapeutic target may be the ability to reweight evidence, not the ability to feel every signal more strongly.

Return to the public explanation

Inference boundary

Evidence that precision change causally mediates clinical recovery is emerging and not yet sufficient for broad treatment claims.

Status and counterevidence

experimental_evidenceR34, R91-R95, R98-R100

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

9 linked sources — open details
R34EMERGING EVIDENCE

Transdiagnostic failure to adapt interoceptive precision estimates across affective, substance use, and eating disorders: replication and extension

Lavalley CA et al

Claim boundary: Evidence that precision change causally mediates clinical recovery is emerging and not yet sufficient for broad treatment claims.

Publication record
R91EMERGING EVIDENCE

Interoceptive technologies for psychiatric interventions: from diagnosis to clinical applications

Schoeller F et al

Claim boundary: Evidence that precision change causally mediates clinical recovery is emerging and not yet sufficient for broad treatment claims.

Publication record
R92EMERGING EVIDENCE

Heart rate variability biofeedback: how and why does it work?

Lehrer PM, Gevirtz R

Claim boundary: Evidence that precision change causally mediates clinical recovery is emerging and not yet sufficient for broad treatment claims.

Publication record
R93EMERGING EVIDENCE

Real-time fMRI neurofeedback boosts heartbeat perception by modulating insula activation during interoceptive attention

Haruki Y et al

Claim boundary: Evidence that precision change causally mediates clinical recovery is emerging and not yet sufficient for broad treatment claims.

Publication record
R94EMERGING EVIDENCE

Transcutaneous auricular vagus nerve stimulation modulates interoceptive prediction-error processing and allostatic regulation

Ventura-Bort C, Weymar M

Claim boundary: Evidence that precision change causally mediates clinical recovery is emerging and not yet sufficient for broad treatment claims.

Publication record
R95EMERGING EVIDENCE

A systematic review of associations between interoception, vagal tone, and emotional regulation

Pinna T, Edwards DJ

Claim boundary: Evidence that precision change causally mediates clinical recovery is emerging and not yet sufficient for broad treatment claims.

Publication record
R98EMERGING EVIDENCE

Systematic review and meta-analysis of the relationship between heartbeat-evoked potential and interoception

Coll MP et al

Claim boundary: Evidence that precision change causally mediates clinical recovery is emerging and not yet sufficient for broad treatment claims.

Publication record
R99EMERGING EVIDENCE

The respiratory resistance sensitivity task: quantifying respiratory interoception and metacognition

Nikolova N et al

Claim boundary: Evidence that precision change causally mediates clinical recovery is emerging and not yet sufficient for broad treatment claims.

Publication record
R100EMERGING EVIDENCE

The heart rate discrimination task: estimating accuracy and precision of interoceptive beliefs

Legrand N et al

Claim boundary: Evidence that precision change causally mediates clinical recovery is emerging and not yet sufficient for broad treatment claims.

Publication record
C19

SUPPORTED INTERPRETATION · conditional_evidence · LECTURE PAGE 30

Emotion is embodied meaning: physiology interpreted inside a history, context and field of possible action.

What the map supports

Emotion is embodied meaning: physiology interpreted inside a history, context and field of possible action.

Return to the public explanation

Inference boundary

The lecture does not endorse a unique peripheral signature for each emotion or claim that cognition merely labels pre-existing bodily states.

Status and counterevidence

conditional_evidenceR05, R12-R14, R27-R28

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

6 linked sources — open details
R05SUPPORTED INTERPRETATION

Interoception and emotion

Critchley HD, Garfinkel SN

Claim boundary: The lecture does not endorse a unique peripheral signature for each emotion or claim that cognition merely labels pre-existing bodily states.

Publication record
R12SUPPORTED INTERPRETATION

Saliency, switching, attention and control: a network model of insula function

Menon V, Uddin LQ

Claim boundary: The lecture does not endorse a unique peripheral signature for each emotion or claim that cognition merely labels pre-existing bodily states.

Publication record
R13SUPPORTED INTERPRETATION

Interoceptive rhythms in the brain

Engelen T, Solca M, Tallon-Baudry C

Claim boundary: The lecture does not endorse a unique peripheral signature for each emotion or claim that cognition merely labels pre-existing bodily states.

Publication record
R14SUPPORTED INTERPRETATION

Physiological feelings

Pace-Schott EF et al

Claim boundary: The lecture does not endorse a unique peripheral signature for each emotion or claim that cognition merely labels pre-existing bodily states.

Publication record
R27SUPPORTED INTERPRETATION

Interoceptive predictions in the brain

Barrett LF, Simmons WK

Claim boundary: The lecture does not endorse a unique peripheral signature for each emotion or claim that cognition merely labels pre-existing bodily states.

Publication record
R28SUPPORTED INTERPRETATION

The theory of constructed emotion: an active inference account of interoception and categorization

Barrett LF

Claim boundary: The lecture does not endorse a unique peripheral signature for each emotion or claim that cognition merely labels pre-existing bodily states.

Publication record
C20

SUPPORTED INTERPRETATION · conditional_evidence · LECTURE PAGE 31

When every internal difficulty feels like the same emergency, the same emergency solution becomes easier to repeat.

What the map supports

When every internal difficulty feels like the same emergency, the same emergency solution becomes easier to repeat.

Return to the public explanation

Inference boundary

Alexithymia is not equivalent to poor interoception, and self-report measures can confound emotional vocabulary with bodily accuracy.

Status and counterevidence

conditional_evidenceR41, R49, R67

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

3 linked sources — open details
R41SUPPORTED INTERPRETATION

Atypical interoception as a common risk factor for psychopathology: a review

Brewer R, Murphy J, Bird G

Claim boundary: Alexithymia is not equivalent to poor interoception, and self-report measures can confound emotional vocabulary with bodily accuracy.

Publication record
R49SUPPORTED INTERPRETATION

Interoception abnormalities in schizophrenia: review and integration with Bayesian accounts of psychosis

Yao B, Thakkar KN

Claim boundary: Alexithymia is not equivalent to poor interoception, and self-report measures can confound emotional vocabulary with bodily accuracy.

Publication record
R67SUPPORTED INTERPRETATION

Interoception and psychopathology: a developmental neuroscience perspective

Murphy J, Brewer R, Catmur C, Bird G

Claim boundary: Alexithymia is not equivalent to poor interoception, and self-report measures can confound emotional vocabulary with bodily accuracy.

Publication record
C21

FLOW HIJACKED SYNTHESIS · flow_hijacked_synthesis · LECTURE PAGE 32

Feelings matter partly because they redraw the map of what the person can do next.

What the map supports

Feelings matter partly because they redraw the map of what the person can do next.

Return to the public explanation

Inference boundary

The language of reachability is a Flow Hijacked formalization, not a validated clinical metric of emotion.

Status and counterevidence

flow_hijacked_synthesisR24-R32, R37-R40

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

13 linked sources — open details
R24FLOW HIJACKED SYNTHESIS

Uncertainty and stress: why it causes diseases and how it is mastered by the brain

Peters A, McEwen BS, Friston K

Claim boundary: The language of reachability is a Flow Hijacked formalization, not a validated clinical metric of emotion.

Publication record
R25FLOW HIJACKED SYNTHESIS

Active inference, homeostatic regulation and adaptive behavioural control

Pezzulo G, Rigoli F, Friston K

Claim boundary: The language of reachability is a Flow Hijacked formalization, not a validated clinical metric of emotion.

Publication record
R26FLOW HIJACKED SYNTHESIS

Active interoceptive inference and the emotional brain

Seth AK, Friston KJ

Claim boundary: The language of reachability is a Flow Hijacked formalization, not a validated clinical metric of emotion.

Publication record
R27FLOW HIJACKED SYNTHESIS

Interoceptive predictions in the brain

Barrett LF, Simmons WK

Claim boundary: The language of reachability is a Flow Hijacked formalization, not a validated clinical metric of emotion.

Publication record
R28FLOW HIJACKED SYNTHESIS

The theory of constructed emotion: an active inference account of interoception and categorization

Barrett LF

Claim boundary: The language of reachability is a Flow Hijacked formalization, not a validated clinical metric of emotion.

Publication record
R29FLOW HIJACKED SYNTHESIS

Interoceptive inference: from computational neuroscience to clinic

Owens AP, Allen M, Ondobaka S, Friston K

Claim boundary: The language of reachability is a Flow Hijacked formalization, not a validated clinical metric of emotion.

Publication record
R30FLOW HIJACKED SYNTHESIS

An Active Inference Approach to Interoceptive Psychopathology

Paulus MP, Feinstein JS, Khalsa SS

Claim boundary: The language of reachability is a Flow Hijacked formalization, not a validated clinical metric of emotion.

Publication record
R31FLOW HIJACKED SYNTHESIS

Computational psychosomatics and computational psychiatry: toward a joint framework for differential diagnosis

Petzschner FH, Weber LAE, Gard T, Stephan KE

Claim boundary: The language of reachability is a Flow Hijacked formalization, not a validated clinical metric of emotion.

Publication record
R32FLOW HIJACKED SYNTHESIS

Allostatic Self-efficacy: a metacognitive theory of dyshomeostasis-induced fatigue and depression

Stephan KE et al

Claim boundary: The language of reachability is a Flow Hijacked formalization, not a validated clinical metric of emotion.

Publication record
R37FLOW HIJACKED SYNTHESIS

Interoception as modeling, allostasis as control

Sennesh E et al

Claim boundary: The language of reachability is a Flow Hijacked formalization, not a validated clinical metric of emotion.

Publication record
R38FLOW HIJACKED SYNTHESIS

Allostasis as a core feature of hierarchical gradients in the human brain

Katsumi Y et al

Claim boundary: The language of reachability is a Flow Hijacked formalization, not a validated clinical metric of emotion.

Publication record
R39FLOW HIJACKED SYNTHESIS

Intrinsic timescales and predictive allostatic interoception in brain health and disease

Ibanez A, Northoff G

Claim boundary: The language of reachability is a Flow Hijacked formalization, not a validated clinical metric of emotion.

Publication record
R40FLOW HIJACKED SYNTHESIS

The energetic cost of allostasis and allostatic load

Bobba-Alves N, Juster RP, Picard M

Claim boundary: The language of reachability is a Flow Hijacked formalization, not a validated clinical metric of emotion.

Publication record
C22

SUPPORTED INTERPRETATION · conditional_evidence · LECTURE PAGE 34

The self is not located in the body, but every self must continuously negotiate being a body.

What the map supports

The self is not located in the body, but every self must continuously negotiate being a body.

Return to the public explanation

Inference boundary

Bodily self-consciousness is multisensory; interoception is one contributor among vision, touch, proprioception, vestibular signals, memory and social cognition.

Status and counterevidence

conditional_evidenceR13-R15, R50-R52

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

6 linked sources — open details
R13SUPPORTED INTERPRETATION

Interoceptive rhythms in the brain

Engelen T, Solca M, Tallon-Baudry C

Claim boundary: Bodily self-consciousness is multisensory; interoception is one contributor among vision, touch, proprioception, vestibular signals, memory and social cognition.

Publication record
R14SUPPORTED INTERPRETATION

Physiological feelings

Pace-Schott EF et al

Claim boundary: Bodily self-consciousness is multisensory; interoception is one contributor among vision, touch, proprioception, vestibular signals, memory and social cognition.

Publication record
R15SUPPORTED INTERPRETATION

The functional role of cardiac activity in perception and action

Skora L, Livermore JJA, Roelofs K

Claim boundary: Bodily self-consciousness is multisensory; interoception is one contributor among vision, touch, proprioception, vestibular signals, memory and social cognition.

Publication record
R50SUPPORTED INTERPRETATION

A roadmap to understanding interoceptive awareness and post-traumatic stress disorder: a scoping review

Leech K, Stapleton P, Patching A

Claim boundary: Bodily self-consciousness is multisensory; interoception is one contributor among vision, touch, proprioception, vestibular signals, memory and social cognition.

Publication record
R51SUPPORTED INTERPRETATION

The brain-body disconnect: a somatic sensory basis for trauma-related disorders

Kearney BE, Lanius RA

Claim boundary: Bodily self-consciousness is multisensory; interoception is one contributor among vision, touch, proprioception, vestibular signals, memory and social cognition.

Publication record
R52SUPPORTED INTERPRETATION

How processing of internal and external sensory information shapes engagement with the world after trauma

Harricharan S, McKinnon MC, Lanius RA

Claim boundary: Bodily self-consciousness is multisensory; interoception is one contributor among vision, touch, proprioception, vestibular signals, memory and social cognition.

Publication record
C23

FLOW HIJACKED SYNTHESIS · flow_hijacked_synthesis · LECTURE PAGE 35

Agency grows when the system can predict that more than one action is capable of moving it.

What the map supports

Agency grows when the system can predict that more than one action is capable of moving it.

Return to the public explanation

Inference boundary

The control-theoretic language is explanatory; individual agency cannot be inferred from one physiological or computational measure.

Status and counterevidence

flow_hijacked_synthesisR25, R32, R37, R65-R66

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

5 linked sources — open details
R25FLOW HIJACKED SYNTHESIS

Active inference, homeostatic regulation and adaptive behavioural control

Pezzulo G, Rigoli F, Friston K

Claim boundary: The control-theoretic language is explanatory; individual agency cannot be inferred from one physiological or computational measure.

Publication record
R32FLOW HIJACKED SYNTHESIS

Allostatic Self-efficacy: a metacognitive theory of dyshomeostasis-induced fatigue and depression

Stephan KE et al

Claim boundary: The control-theoretic language is explanatory; individual agency cannot be inferred from one physiological or computational measure.

Publication record
R37FLOW HIJACKED SYNTHESIS

Interoception as modeling, allostasis as control

Sennesh E et al

Claim boundary: The control-theoretic language is explanatory; individual agency cannot be inferred from one physiological or computational measure.

Publication record
R65FLOW HIJACKED SYNTHESIS

Neurobiology of eating behavior, nutrition, and health

Stover PJ et al

Claim boundary: The control-theoretic language is explanatory; individual agency cannot be inferred from one physiological or computational measure.

Publication record
R66FLOW HIJACKED SYNTHESIS

Heterogeneous appetite patterns in depression: computational modeling of nutritional interoception, reward processing, and decision-making

Uchida Y et al

Claim boundary: The control-theoretic language is explanatory; individual agency cannot be inferred from one physiological or computational measure.

Publication record
C24

SUPPORTED INTERPRETATION · conditional_evidence · LECTURE PAGE 36

The body gives the present a history before the mind tells the story of that history.

What the map supports

The body gives the present a history before the mind tells the story of that history.

Return to the public explanation

Inference boundary

History dependence does not imply permanence. Biological and learned processes operate on multiple reversible and irreversible timescales.

Status and counterevidence

conditional_evidenceR13, R23-R24, R35, R39-R40

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

6 linked sources — open details
R13SUPPORTED INTERPRETATION

Interoceptive rhythms in the brain

Engelen T, Solca M, Tallon-Baudry C

Claim boundary: History dependence does not imply permanence. Biological and learned processes operate on multiple reversible and irreversible timescales.

Publication record
R23SUPPORTED INTERPRETATION

Stress, adaptation, and disease: allostasis and allostatic load

McEwen BS

Claim boundary: History dependence does not imply permanence. Biological and learned processes operate on multiple reversible and irreversible timescales.

Publication record
R24SUPPORTED INTERPRETATION

Uncertainty and stress: why it causes diseases and how it is mastered by the brain

Peters A, McEwen BS, Friston K

Claim boundary: History dependence does not imply permanence. Biological and learned processes operate on multiple reversible and irreversible timescales.

Publication record
R35SUPPORTED INTERPRETATION

Allostatic interoceptive overload across psychiatric and neurological conditions

Santamaria-Garcia H et al

Claim boundary: History dependence does not imply permanence. Biological and learned processes operate on multiple reversible and irreversible timescales.

Publication record
R39SUPPORTED INTERPRETATION

Intrinsic timescales and predictive allostatic interoception in brain health and disease

Ibanez A, Northoff G

Claim boundary: History dependence does not imply permanence. Biological and learned processes operate on multiple reversible and irreversible timescales.

Publication record
R40SUPPORTED INTERPRETATION

The energetic cost of allostasis and allostatic load

Bobba-Alves N, Juster RP, Picard M

Claim boundary: History dependence does not imply permanence. Biological and learned processes operate on multiple reversible and irreversible timescales.

Publication record
C25

SUPPORTED INTERPRETATION · conditional_evidence · LECTURE PAGE 38

A stress system can be powerful at mobilization and weak at return.

What the map supports

A stress system can be powerful at mobilization and weak at return.

Return to the public explanation

Inference boundary

No single biomarker defines stress or safety. Cortisol, HRV and inflammatory markers each index limited components of a larger response.

Status and counterevidence

conditional_evidenceR22-R24, R35, R40, R52

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

6 linked sources — open details
R22SUPPORTED INTERPRETATION

Stress and the individual: mechanisms leading to disease

McEwen BS, Stellar E

Claim boundary: No single biomarker defines stress or safety. Cortisol, HRV and inflammatory markers each index limited components of a larger response.

Publication record
R23SUPPORTED INTERPRETATION

Stress, adaptation, and disease: allostasis and allostatic load

McEwen BS

Claim boundary: No single biomarker defines stress or safety. Cortisol, HRV and inflammatory markers each index limited components of a larger response.

Publication record
R24SUPPORTED INTERPRETATION

Uncertainty and stress: why it causes diseases and how it is mastered by the brain

Peters A, McEwen BS, Friston K

Claim boundary: No single biomarker defines stress or safety. Cortisol, HRV and inflammatory markers each index limited components of a larger response.

Publication record
R35SUPPORTED INTERPRETATION

Allostatic interoceptive overload across psychiatric and neurological conditions

Santamaria-Garcia H et al

Claim boundary: No single biomarker defines stress or safety. Cortisol, HRV and inflammatory markers each index limited components of a larger response.

Publication record
R40SUPPORTED INTERPRETATION

The energetic cost of allostasis and allostatic load

Bobba-Alves N, Juster RP, Picard M

Claim boundary: No single biomarker defines stress or safety. Cortisol, HRV and inflammatory markers each index limited components of a larger response.

Publication record
R52SUPPORTED INTERPRETATION

How processing of internal and external sensory information shapes engagement with the world after trauma

Harricharan S, McKinnon MC, Lanius RA

Claim boundary: No single biomarker defines stress or safety. Cortisol, HRV and inflammatory markers each index limited components of a larger response.

Publication record
C26

SUPPORTED INTERPRETATION · conditional_evidence · LECTURE PAGE 39

A nervous system learns the cost of uncertainty from the environments in which it had to survive uncertainty.

What the map supports

A nervous system learns the cost of uncertainty from the environments in which it had to survive uncertainty.

Return to the public explanation

Inference boundary

Developmental effects are probabilistic, not destiny; retrospective adversity measures and causal inference have important limitations.

Status and counterevidence

conditional_evidenceR67-R77

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

11 linked sources — open details
R67SUPPORTED INTERPRETATION

Interoception and psychopathology: a developmental neuroscience perspective

Murphy J, Brewer R, Catmur C, Bird G

Claim boundary: Developmental effects are probabilistic, not destiny; retrospective adversity measures and causal inference have important limitations.

Publication record
R68SUPPORTED INTERPRETATION

Being in Tune With Your Body: the emergence of interoceptive processing through caregiver-infant feeding interactions

Filippetti ML

Claim boundary: Developmental effects are probabilistic, not destiny; retrospective adversity measures and causal inference have important limitations.

Publication record
R69SUPPORTED INTERPRETATION

The body comes first: embodied reparation and the co-creation of infant bodily-self

Montirosso R, McGlone F

Claim boundary: Developmental effects are probabilistic, not destiny; retrospective adversity measures and causal inference have important limitations.

Publication record
R70SUPPORTED INTERPRETATION

Affective regulation through touch: homeostatic and allostatic mechanisms

Fotopoulou A, von Mohr M, Krahe C

Claim boundary: Developmental effects are probabilistic, not destiny; retrospective adversity measures and causal inference have important limitations.

Publication record
R71SUPPORTED INTERPRETATION

Developmental perspectives on interpersonal affective touch

Crucianelli L, Filippetti ML

Claim boundary: Developmental effects are probabilistic, not destiny; retrospective adversity measures and causal inference have important limitations.

Publication record
R72SUPPORTED INTERPRETATION

What are C-tactile afferents and how do they relate to affective touch?

Schirmer A, Croy I, Ackerley R

Claim boundary: Developmental effects are probabilistic, not destiny; retrospective adversity measures and causal inference have important limitations.

Publication record
R73SUPPORTED INTERPRETATION

Keep Calm and Cuddle On: social touch as a stress buffer

Morrison I

Claim boundary: Developmental effects are probabilistic, not destiny; retrospective adversity measures and causal inference have important limitations.

Publication record
R74SUPPORTED INTERPRETATION

Interactive synchrony and infants’ vagal tone as an index of emotion regulation

Puglisi N et al

Claim boundary: Developmental effects are probabilistic, not destiny; retrospective adversity measures and causal inference have important limitations.

Publication record
R75SUPPORTED INTERPRETATION

A Developmental Framework of Interpersonal Neural Synchrony

Hoehl S et al

Claim boundary: Developmental effects are probabilistic, not destiny; retrospective adversity measures and causal inference have important limitations.

Publication record
R76SUPPORTED INTERPRETATION

Social Baseline Theory: the social regulation of risk and effort

Coan JA, Sbarra DA

Claim boundary: Developmental effects are probabilistic, not destiny; retrospective adversity measures and causal inference have important limitations.

Publication record
R77SUPPORTED INTERPRETATION

Health neuroscience 2.0: integration with social, cognitive and affective neuroscience

Inagaki TK

Claim boundary: Developmental effects are probabilistic, not destiny; retrospective adversity measures and causal inference have important limitations.

Publication record
C27

FLOW HIJACKED SYNTHESIS · flow_hijacked_synthesis · LECTURE PAGE 40

The past survives when present-day regulation keeps recreating the conditions under which the old model remains plausible.

What the map supports

The past survives when present-day regulation keeps recreating the conditions under which the old model remains plausible.

Return to the public explanation

Inference boundary

The attractor interpretation is a Flow Hijacked synthesis. Individual symptoms can persist for many reasons not captured by this loop.

Status and counterevidence

flow_hijacked_synthesisR24-R31, R41-R57

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

25 linked sources — open details
R24FLOW HIJACKED SYNTHESIS

Uncertainty and stress: why it causes diseases and how it is mastered by the brain

Peters A, McEwen BS, Friston K

Claim boundary: The attractor interpretation is a Flow Hijacked synthesis. Individual symptoms can persist for many reasons not captured by this loop.

Publication record
R25FLOW HIJACKED SYNTHESIS

Active inference, homeostatic regulation and adaptive behavioural control

Pezzulo G, Rigoli F, Friston K

Claim boundary: The attractor interpretation is a Flow Hijacked synthesis. Individual symptoms can persist for many reasons not captured by this loop.

Publication record
R26FLOW HIJACKED SYNTHESIS

Active interoceptive inference and the emotional brain

Seth AK, Friston KJ

Claim boundary: The attractor interpretation is a Flow Hijacked synthesis. Individual symptoms can persist for many reasons not captured by this loop.

Publication record
R27FLOW HIJACKED SYNTHESIS

Interoceptive predictions in the brain

Barrett LF, Simmons WK

Claim boundary: The attractor interpretation is a Flow Hijacked synthesis. Individual symptoms can persist for many reasons not captured by this loop.

Publication record
R28FLOW HIJACKED SYNTHESIS

The theory of constructed emotion: an active inference account of interoception and categorization

Barrett LF

Claim boundary: The attractor interpretation is a Flow Hijacked synthesis. Individual symptoms can persist for many reasons not captured by this loop.

Publication record
R29FLOW HIJACKED SYNTHESIS

Interoceptive inference: from computational neuroscience to clinic

Owens AP, Allen M, Ondobaka S, Friston K

Claim boundary: The attractor interpretation is a Flow Hijacked synthesis. Individual symptoms can persist for many reasons not captured by this loop.

Publication record
R30FLOW HIJACKED SYNTHESIS

An Active Inference Approach to Interoceptive Psychopathology

Paulus MP, Feinstein JS, Khalsa SS

Claim boundary: The attractor interpretation is a Flow Hijacked synthesis. Individual symptoms can persist for many reasons not captured by this loop.

Publication record
R31FLOW HIJACKED SYNTHESIS

Computational psychosomatics and computational psychiatry: toward a joint framework for differential diagnosis

Petzschner FH, Weber LAE, Gard T, Stephan KE

Claim boundary: The attractor interpretation is a Flow Hijacked synthesis. Individual symptoms can persist for many reasons not captured by this loop.

Publication record
R41FLOW HIJACKED SYNTHESIS

Atypical interoception as a common risk factor for psychopathology: a review

Brewer R, Murphy J, Bird G

Claim boundary: The attractor interpretation is a Flow Hijacked synthesis. Individual symptoms can persist for many reasons not captured by this loop.

Publication record
R42FLOW HIJACKED SYNTHESIS

Common threads: altered interoceptive processes across affective and anxiety disorders

Saltafossi M, Heck D, Kluger DS, Varga S

Claim boundary: The attractor interpretation is a Flow Hijacked synthesis. Individual symptoms can persist for many reasons not captured by this loop.

Publication record
R43FLOW HIJACKED SYNTHESIS

Interoception in anxiety, depression, and psychosis: a review

Jenkinson PM, Fotopoulou A, Ibanez A, Rossell SL

Claim boundary: The attractor interpretation is a Flow Hijacked synthesis. Individual symptoms can persist for many reasons not captured by this loop.

Publication record
R44FLOW HIJACKED SYNTHESIS

Major depressive disorder is associated with impaired interoceptive accuracy: a systematic review

Eggart M et al

Claim boundary: The attractor interpretation is a Flow Hijacked synthesis. Individual symptoms can persist for many reasons not captured by this loop.

Publication record
R45FLOW HIJACKED SYNTHESIS

Interoceptive Processing in Substance Use Disorders: from neuroanatomy to computational models and predictive coding

Paulus MP

Claim boundary: The attractor interpretation is a Flow Hijacked synthesis. Individual symptoms can persist for many reasons not captured by this loop.

Publication record
R46FLOW HIJACKED SYNTHESIS

A Systematic Review of Interoception in Substance Use Disorders

Im JJ et al

Claim boundary: The attractor interpretation is a Flow Hijacked synthesis. Individual symptoms can persist for many reasons not captured by this loop.

Publication record
R47FLOW HIJACKED SYNTHESIS

Gastrointestinal Interoception in Eating Disorders: Charting a New Path

Khalsa SS, Berner LA, Anderson LM

Claim boundary: The attractor interpretation is a Flow Hijacked synthesis. Individual symptoms can persist for many reasons not captured by this loop.

Publication record
R48FLOW HIJACKED SYNTHESIS

Interoception and Obsessive-Compulsive Disorder: a review of current evidence and future directions

Bragdon LB et al

Claim boundary: The attractor interpretation is a Flow Hijacked synthesis. Individual symptoms can persist for many reasons not captured by this loop.

Publication record
R49FLOW HIJACKED SYNTHESIS

Interoception abnormalities in schizophrenia: review and integration with Bayesian accounts of psychosis

Yao B, Thakkar KN

Claim boundary: The attractor interpretation is a Flow Hijacked synthesis. Individual symptoms can persist for many reasons not captured by this loop.

Publication record
R50FLOW HIJACKED SYNTHESIS

A roadmap to understanding interoceptive awareness and post-traumatic stress disorder: a scoping review

Leech K, Stapleton P, Patching A

Claim boundary: The attractor interpretation is a Flow Hijacked synthesis. Individual symptoms can persist for many reasons not captured by this loop.

Publication record
R51FLOW HIJACKED SYNTHESIS

The brain-body disconnect: a somatic sensory basis for trauma-related disorders

Kearney BE, Lanius RA

Claim boundary: The attractor interpretation is a Flow Hijacked synthesis. Individual symptoms can persist for many reasons not captured by this loop.

Publication record
R52FLOW HIJACKED SYNTHESIS

How processing of internal and external sensory information shapes engagement with the world after trauma

Harricharan S, McKinnon MC, Lanius RA

Claim boundary: The attractor interpretation is a Flow Hijacked synthesis. Individual symptoms can persist for many reasons not captured by this loop.

Publication record
R53FLOW HIJACKED SYNTHESIS

Perceptual insensitivity to the modulation of interoceptive signals in depression, anxiety, and substance use disorders

Smith R et al

Claim boundary: The attractor interpretation is a Flow Hijacked synthesis. Individual symptoms can persist for many reasons not captured by this loop.

Publication record
R54FLOW HIJACKED SYNTHESIS

Cardiac interoception in patients accessing secondary mental health services: a transdiagnostic study

Critchley HD et al

Claim boundary: The attractor interpretation is a Flow Hijacked synthesis. Individual symptoms can persist for many reasons not captured by this loop.

Publication record
R55FLOW HIJACKED SYNTHESIS

Insular dysfunction of interoception in major depressive disorder: a neuroimaging perspective

Hu L et al

Claim boundary: The attractor interpretation is a Flow Hijacked synthesis. Individual symptoms can persist for many reasons not captured by this loop.

Publication record
R56FLOW HIJACKED SYNTHESIS

Insula-cerebellar functional connectivity associated with somatic symptoms in mood disorders

Hattori S et al

Claim boundary: The attractor interpretation is a Flow Hijacked synthesis. Individual symptoms can persist for many reasons not captured by this loop.

Publication record
R57FLOW HIJACKED SYNTHESIS

Interoceptive ability is uncorrelated across respiratory and cardiac axes in a large-scale psychophysical study

Banellis L et al

Claim boundary: The attractor interpretation is a Flow Hijacked synthesis. Individual symptoms can persist for many reasons not captured by this loop.

Publication record
C28

SUPPORTED INTERPRETATION · conditional_evidence · LECTURE PAGE 42

Panic is not the presence of bodily change. It is a learned regime in which bodily change can become a privileged route into danger.

What the map supports

Panic is not the presence of bodily change. It is a learned regime in which bodily change can become a privileged route into danger.

Return to the public explanation

Inference boundary

Bodily arousal is not inherently pathological, and panic cannot be diagnosed from interoceptive performance or autonomic measures.

Status and counterevidence

conditional_evidenceR42-R44, R53, R99

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

5 linked sources — open details
R42SUPPORTED INTERPRETATION

Common threads: altered interoceptive processes across affective and anxiety disorders

Saltafossi M, Heck D, Kluger DS, Varga S

Claim boundary: Bodily arousal is not inherently pathological, and panic cannot be diagnosed from interoceptive performance or autonomic measures.

Publication record
R43SUPPORTED INTERPRETATION

Interoception in anxiety, depression, and psychosis: a review

Jenkinson PM, Fotopoulou A, Ibanez A, Rossell SL

Claim boundary: Bodily arousal is not inherently pathological, and panic cannot be diagnosed from interoceptive performance or autonomic measures.

Publication record
R44SUPPORTED INTERPRETATION

Major depressive disorder is associated with impaired interoceptive accuracy: a systematic review

Eggart M et al

Claim boundary: Bodily arousal is not inherently pathological, and panic cannot be diagnosed from interoceptive performance or autonomic measures.

Publication record
R53SUPPORTED INTERPRETATION

Perceptual insensitivity to the modulation of interoceptive signals in depression, anxiety, and substance use disorders

Smith R et al

Claim boundary: Bodily arousal is not inherently pathological, and panic cannot be diagnosed from interoceptive performance or autonomic measures.

Publication record
R99SUPPORTED INTERPRETATION

The respiratory resistance sensitivity task: quantifying respiratory interoception and metacognition

Nikolova N et al

Claim boundary: Bodily arousal is not inherently pathological, and panic cannot be diagnosed from interoceptive performance or autonomic measures.

Publication record
C29

SUPPORTED INTERPRETATION · conditional_evidence · LECTURE PAGE 43

Depression can narrow the future partly by making movement feel biologically and computationally expensive.

What the map supports

Depression can narrow the future partly by making movement feel biologically and computationally expensive.

Return to the public explanation

Inference boundary

The lecture does not claim that depression is caused by low energy, inflammation or interoceptive error; these are heterogeneous contributors and candidate mechanisms.

Status and counterevidence

conditional_evidenceR32, R35, R43-R46, R55-R56, R65-R66

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

10 linked sources — open details
R32SUPPORTED INTERPRETATION

Allostatic Self-efficacy: a metacognitive theory of dyshomeostasis-induced fatigue and depression

Stephan KE et al

Claim boundary: The lecture does not claim that depression is caused by low energy, inflammation or interoceptive error; these are heterogeneous contributors and candidate mechanisms.

Publication record
R35SUPPORTED INTERPRETATION

Allostatic interoceptive overload across psychiatric and neurological conditions

Santamaria-Garcia H et al

Claim boundary: The lecture does not claim that depression is caused by low energy, inflammation or interoceptive error; these are heterogeneous contributors and candidate mechanisms.

Publication record
R43SUPPORTED INTERPRETATION

Interoception in anxiety, depression, and psychosis: a review

Jenkinson PM, Fotopoulou A, Ibanez A, Rossell SL

Claim boundary: The lecture does not claim that depression is caused by low energy, inflammation or interoceptive error; these are heterogeneous contributors and candidate mechanisms.

Publication record
R44SUPPORTED INTERPRETATION

Major depressive disorder is associated with impaired interoceptive accuracy: a systematic review

Eggart M et al

Claim boundary: The lecture does not claim that depression is caused by low energy, inflammation or interoceptive error; these are heterogeneous contributors and candidate mechanisms.

Publication record
R45SUPPORTED INTERPRETATION

Interoceptive Processing in Substance Use Disorders: from neuroanatomy to computational models and predictive coding

Paulus MP

Claim boundary: The lecture does not claim that depression is caused by low energy, inflammation or interoceptive error; these are heterogeneous contributors and candidate mechanisms.

Publication record
R46SUPPORTED INTERPRETATION

A Systematic Review of Interoception in Substance Use Disorders

Im JJ et al

Claim boundary: The lecture does not claim that depression is caused by low energy, inflammation or interoceptive error; these are heterogeneous contributors and candidate mechanisms.

Publication record
R55SUPPORTED INTERPRETATION

Insular dysfunction of interoception in major depressive disorder: a neuroimaging perspective

Hu L et al

Claim boundary: The lecture does not claim that depression is caused by low energy, inflammation or interoceptive error; these are heterogeneous contributors and candidate mechanisms.

Publication record
R56SUPPORTED INTERPRETATION

Insula-cerebellar functional connectivity associated with somatic symptoms in mood disorders

Hattori S et al

Claim boundary: The lecture does not claim that depression is caused by low energy, inflammation or interoceptive error; these are heterogeneous contributors and candidate mechanisms.

Publication record
R65SUPPORTED INTERPRETATION

Neurobiology of eating behavior, nutrition, and health

Stover PJ et al

Claim boundary: The lecture does not claim that depression is caused by low energy, inflammation or interoceptive error; these are heterogeneous contributors and candidate mechanisms.

Publication record
R66SUPPORTED INTERPRETATION

Heterogeneous appetite patterns in depression: computational modeling of nutritional interoception, reward processing, and decision-making

Uchida Y et al

Claim boundary: The lecture does not claim that depression is caused by low energy, inflammation or interoceptive error; these are heterogeneous contributors and candidate mechanisms.

Publication record
C30

SUPPORTED INTERPRETATION · conditional_evidence · LECTURE PAGE 44

A shared dynamical question can connect disorders without pretending they are the same disorder.

What the map supports

A shared dynamical question can connect disorders without pretending they are the same disorder.

Return to the public explanation

Inference boundary

Transdiagnostic similarity does not erase diagnosis-specific mechanisms, developmental pathways or treatment evidence.

Status and counterevidence

conditional_evidenceR49-R60

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

12 linked sources — open details
R49SUPPORTED INTERPRETATION

Interoception abnormalities in schizophrenia: review and integration with Bayesian accounts of psychosis

Yao B, Thakkar KN

Claim boundary: Transdiagnostic similarity does not erase diagnosis-specific mechanisms, developmental pathways or treatment evidence.

Publication record
R50SUPPORTED INTERPRETATION

A roadmap to understanding interoceptive awareness and post-traumatic stress disorder: a scoping review

Leech K, Stapleton P, Patching A

Claim boundary: Transdiagnostic similarity does not erase diagnosis-specific mechanisms, developmental pathways or treatment evidence.

Publication record
R51SUPPORTED INTERPRETATION

The brain-body disconnect: a somatic sensory basis for trauma-related disorders

Kearney BE, Lanius RA

Claim boundary: Transdiagnostic similarity does not erase diagnosis-specific mechanisms, developmental pathways or treatment evidence.

Publication record
R52SUPPORTED INTERPRETATION

How processing of internal and external sensory information shapes engagement with the world after trauma

Harricharan S, McKinnon MC, Lanius RA

Claim boundary: Transdiagnostic similarity does not erase diagnosis-specific mechanisms, developmental pathways or treatment evidence.

Publication record
R53SUPPORTED INTERPRETATION

Perceptual insensitivity to the modulation of interoceptive signals in depression, anxiety, and substance use disorders

Smith R et al

Claim boundary: Transdiagnostic similarity does not erase diagnosis-specific mechanisms, developmental pathways or treatment evidence.

Publication record
R54SUPPORTED INTERPRETATION

Cardiac interoception in patients accessing secondary mental health services: a transdiagnostic study

Critchley HD et al

Claim boundary: Transdiagnostic similarity does not erase diagnosis-specific mechanisms, developmental pathways or treatment evidence.

Publication record
R55SUPPORTED INTERPRETATION

Insular dysfunction of interoception in major depressive disorder: a neuroimaging perspective

Hu L et al

Claim boundary: Transdiagnostic similarity does not erase diagnosis-specific mechanisms, developmental pathways or treatment evidence.

Publication record
R56SUPPORTED INTERPRETATION

Insula-cerebellar functional connectivity associated with somatic symptoms in mood disorders

Hattori S et al

Claim boundary: Transdiagnostic similarity does not erase diagnosis-specific mechanisms, developmental pathways or treatment evidence.

Publication record
R57SUPPORTED INTERPRETATION

Interoceptive ability is uncorrelated across respiratory and cardiac axes in a large-scale psychophysical study

Banellis L et al

Claim boundary: Transdiagnostic similarity does not erase diagnosis-specific mechanisms, developmental pathways or treatment evidence.

Publication record
R58SUPPORTED INTERPRETATION

Functional neurological disorder: new subtypes and shared mechanisms

Hallett M et al

Claim boundary: Transdiagnostic similarity does not erase diagnosis-specific mechanisms, developmental pathways or treatment evidence.

Publication record
R59SUPPORTED INTERPRETATION

Persistent physical symptoms: definition, genesis, and management

Lowe B et al

Claim boundary: Transdiagnostic similarity does not erase diagnosis-specific mechanisms, developmental pathways or treatment evidence.

Publication record
R60SUPPORTED INTERPRETATION

Persistent Physical Symptoms as Perceptual Dysregulation: a neuropsychobehavioral model and clinical implications

Henningsen P et al

Claim boundary: Transdiagnostic similarity does not erase diagnosis-specific mechanisms, developmental pathways or treatment evidence.

Publication record
C31

SUPPORTED INTERPRETATION · conditional_evidence · LECTURE PAGE 46

Craving becomes powerful when the body predicts not only reward, but rapid exit from the state it is in.

What the map supports

Craving becomes powerful when the body predicts not only reward, but rapid exit from the state it is in.

Return to the public explanation

Inference boundary

Interoceptive models complement rather than replace reward learning, habit, stress, social context and pharmacology in addiction.

Status and counterevidence

conditional_evidenceR45-R46, R61-R66

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

8 linked sources — open details
R45SUPPORTED INTERPRETATION

Interoceptive Processing in Substance Use Disorders: from neuroanatomy to computational models and predictive coding

Paulus MP

Claim boundary: Interoceptive models complement rather than replace reward learning, habit, stress, social context and pharmacology in addiction.

Publication record
R46SUPPORTED INTERPRETATION

A Systematic Review of Interoception in Substance Use Disorders

Im JJ et al

Claim boundary: Interoceptive models complement rather than replace reward learning, habit, stress, social context and pharmacology in addiction.

Publication record
R61SUPPORTED INTERPRETATION

Effect of Pain Reprocessing Therapy vs Placebo and Usual Care for Patients With Chronic Back Pain

Ashar YK et al

Claim boundary: Interoceptive models complement rather than replace reward learning, habit, stress, social context and pharmacology in addiction.

Publication record
R62SUPPORTED INTERPRETATION

Shape shifting pain: chronification of back pain shifts brain representation

Hashmi JA et al

Claim boundary: Interoceptive models complement rather than replace reward learning, habit, stress, social context and pharmacology in addiction.

Publication record
R63SUPPORTED INTERPRETATION

Reward deficiency and anti-reward in pain chronification

Borsook D et al

Claim boundary: Interoceptive models complement rather than replace reward learning, habit, stress, social context and pharmacology in addiction.

Publication record
R64SUPPORTED INTERPRETATION

Beyond the symptom: the biology of fatigue

Raizen DM et al

Claim boundary: Interoceptive models complement rather than replace reward learning, habit, stress, social context and pharmacology in addiction.

Publication record
R65SUPPORTED INTERPRETATION

Neurobiology of eating behavior, nutrition, and health

Stover PJ et al

Claim boundary: Interoceptive models complement rather than replace reward learning, habit, stress, social context and pharmacology in addiction.

Publication record
R66SUPPORTED INTERPRETATION

Heterogeneous appetite patterns in depression: computational modeling of nutritional interoception, reward processing, and decision-making

Uchida Y et al

Claim boundary: Interoceptive models complement rather than replace reward learning, habit, stress, social context and pharmacology in addiction.

Publication record
C32

SUPPORTED INTERPRETATION · conditional_evidence · LECTURE PAGE 47

A policy becomes compulsive when it remains the only action the system trusts at the moment trust matters most.

What the map supports

A policy becomes compulsive when it remains the only action the system trusts at the moment trust matters most.

Return to the public explanation

Inference boundary

Negative reinforcement is prominent in many addictions but does not describe every stage, substance or person.

Status and counterevidence

conditional_evidenceR45-R46, R63-R66

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

6 linked sources — open details
R45SUPPORTED INTERPRETATION

Interoceptive Processing in Substance Use Disorders: from neuroanatomy to computational models and predictive coding

Paulus MP

Claim boundary: Negative reinforcement is prominent in many addictions but does not describe every stage, substance or person.

Publication record
R46SUPPORTED INTERPRETATION

A Systematic Review of Interoception in Substance Use Disorders

Im JJ et al

Claim boundary: Negative reinforcement is prominent in many addictions but does not describe every stage, substance or person.

Publication record
R63SUPPORTED INTERPRETATION

Reward deficiency and anti-reward in pain chronification

Borsook D et al

Claim boundary: Negative reinforcement is prominent in many addictions but does not describe every stage, substance or person.

Publication record
R64SUPPORTED INTERPRETATION

Beyond the symptom: the biology of fatigue

Raizen DM et al

Claim boundary: Negative reinforcement is prominent in many addictions but does not describe every stage, substance or person.

Publication record
R65SUPPORTED INTERPRETATION

Neurobiology of eating behavior, nutrition, and health

Stover PJ et al

Claim boundary: Negative reinforcement is prominent in many addictions but does not describe every stage, substance or person.

Publication record
R66SUPPORTED INTERPRETATION

Heterogeneous appetite patterns in depression: computational modeling of nutritional interoception, reward processing, and decision-making

Uchida Y et al

Claim boundary: Negative reinforcement is prominent in many addictions but does not describe every stage, substance or person.

Publication record
C33

FLOW HIJACKED SYNTHESIS · flow_hijacked_synthesis · LECTURE PAGE 48

Recovery strengthens when the body learns that there is more than one way out.

What the map supports

Recovery strengthens when the body learns that there is more than one way out.

Return to the public explanation

Inference boundary

Regulatory-repertoire language is a Flow Hijacked construct; it is not a validated addiction outcome scale.

Status and counterevidence

flow_hijacked_synthesisR45-R46, R93-R96

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

6 linked sources — open details
R45FLOW HIJACKED SYNTHESIS

Interoceptive Processing in Substance Use Disorders: from neuroanatomy to computational models and predictive coding

Paulus MP

Claim boundary: Regulatory-repertoire language is a Flow Hijacked construct; it is not a validated addiction outcome scale.

Publication record
R46FLOW HIJACKED SYNTHESIS

A Systematic Review of Interoception in Substance Use Disorders

Im JJ et al

Claim boundary: Regulatory-repertoire language is a Flow Hijacked construct; it is not a validated addiction outcome scale.

Publication record
R93FLOW HIJACKED SYNTHESIS

Real-time fMRI neurofeedback boosts heartbeat perception by modulating insula activation during interoceptive attention

Haruki Y et al

Claim boundary: Regulatory-repertoire language is a Flow Hijacked construct; it is not a validated addiction outcome scale.

Publication record
R94FLOW HIJACKED SYNTHESIS

Transcutaneous auricular vagus nerve stimulation modulates interoceptive prediction-error processing and allostatic regulation

Ventura-Bort C, Weymar M

Claim boundary: Regulatory-repertoire language is a Flow Hijacked construct; it is not a validated addiction outcome scale.

Publication record
R95FLOW HIJACKED SYNTHESIS

A systematic review of associations between interoception, vagal tone, and emotional regulation

Pinna T, Edwards DJ

Claim boundary: Regulatory-repertoire language is a Flow Hijacked construct; it is not a validated addiction outcome scale.

Publication record
R96FLOW HIJACKED SYNTHESIS

Interoception, contemplative practice, and health

Farb NAS et al

Claim boundary: Regulatory-repertoire language is a Flow Hijacked construct; it is not a validated addiction outcome scale.

Publication record
C34

SUPPORTED INTERPRETATION · conditional_evidence · LECTURE PAGE 50

The earliest lesson of bodily regulation is often relational: this state can change, and I do not always have to change it alone.

What the map supports

The earliest lesson of bodily regulation is often relational: this state can change, and I do not always have to change it alone.

Return to the public explanation

Inference boundary

Co-regulation should never be used to justify forced touch, dependency, surveillance or the claim that one person can directly control another’s nervous system.

Status and counterevidence

conditional_evidenceR67-R77

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

11 linked sources — open details
R67SUPPORTED INTERPRETATION

Interoception and psychopathology: a developmental neuroscience perspective

Murphy J, Brewer R, Catmur C, Bird G

Claim boundary: Co-regulation should never be used to justify forced touch, dependency, surveillance or the claim that one person can directly control another’s nervous system.

Publication record
R68SUPPORTED INTERPRETATION

Being in Tune With Your Body: the emergence of interoceptive processing through caregiver-infant feeding interactions

Filippetti ML

Claim boundary: Co-regulation should never be used to justify forced touch, dependency, surveillance or the claim that one person can directly control another’s nervous system.

Publication record
R69SUPPORTED INTERPRETATION

The body comes first: embodied reparation and the co-creation of infant bodily-self

Montirosso R, McGlone F

Claim boundary: Co-regulation should never be used to justify forced touch, dependency, surveillance or the claim that one person can directly control another’s nervous system.

Publication record
R70SUPPORTED INTERPRETATION

Affective regulation through touch: homeostatic and allostatic mechanisms

Fotopoulou A, von Mohr M, Krahe C

Claim boundary: Co-regulation should never be used to justify forced touch, dependency, surveillance or the claim that one person can directly control another’s nervous system.

Publication record
R71SUPPORTED INTERPRETATION

Developmental perspectives on interpersonal affective touch

Crucianelli L, Filippetti ML

Claim boundary: Co-regulation should never be used to justify forced touch, dependency, surveillance or the claim that one person can directly control another’s nervous system.

Publication record
R72SUPPORTED INTERPRETATION

What are C-tactile afferents and how do they relate to affective touch?

Schirmer A, Croy I, Ackerley R

Claim boundary: Co-regulation should never be used to justify forced touch, dependency, surveillance or the claim that one person can directly control another’s nervous system.

Publication record
R73SUPPORTED INTERPRETATION

Keep Calm and Cuddle On: social touch as a stress buffer

Morrison I

Claim boundary: Co-regulation should never be used to justify forced touch, dependency, surveillance or the claim that one person can directly control another’s nervous system.

Publication record
R74SUPPORTED INTERPRETATION

Interactive synchrony and infants’ vagal tone as an index of emotion regulation

Puglisi N et al

Claim boundary: Co-regulation should never be used to justify forced touch, dependency, surveillance or the claim that one person can directly control another’s nervous system.

Publication record
R75SUPPORTED INTERPRETATION

A Developmental Framework of Interpersonal Neural Synchrony

Hoehl S et al

Claim boundary: Co-regulation should never be used to justify forced touch, dependency, surveillance or the claim that one person can directly control another’s nervous system.

Publication record
R76SUPPORTED INTERPRETATION

Social Baseline Theory: the social regulation of risk and effort

Coan JA, Sbarra DA

Claim boundary: Co-regulation should never be used to justify forced touch, dependency, surveillance or the claim that one person can directly control another’s nervous system.

Publication record
R77SUPPORTED INTERPRETATION

Health neuroscience 2.0: integration with social, cognitive and affective neuroscience

Inagaki TK

Claim boundary: Co-regulation should never be used to justify forced touch, dependency, surveillance or the claim that one person can directly control another’s nervous system.

Publication record
C35

SUPPORTED INTERPRETATION · conditional_evidence · LECTURE PAGE 51

Another person can change the cost of a transition without taking the transition for us.

What the map supports

Another person can change the cost of a transition without taking the transition for us.

Return to the public explanation

Inference boundary

Social buffering is heterogeneous and cannot be reduced to HRV, oxytocin or one attachment style.

Status and counterevidence

conditional_evidenceR72-R80

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

9 linked sources — open details
R72SUPPORTED INTERPRETATION

What are C-tactile afferents and how do they relate to affective touch?

Schirmer A, Croy I, Ackerley R

Claim boundary: Social buffering is heterogeneous and cannot be reduced to HRV, oxytocin or one attachment style.

Publication record
R73SUPPORTED INTERPRETATION

Keep Calm and Cuddle On: social touch as a stress buffer

Morrison I

Claim boundary: Social buffering is heterogeneous and cannot be reduced to HRV, oxytocin or one attachment style.

Publication record
R74SUPPORTED INTERPRETATION

Interactive synchrony and infants’ vagal tone as an index of emotion regulation

Puglisi N et al

Claim boundary: Social buffering is heterogeneous and cannot be reduced to HRV, oxytocin or one attachment style.

Publication record
R75SUPPORTED INTERPRETATION

A Developmental Framework of Interpersonal Neural Synchrony

Hoehl S et al

Claim boundary: Social buffering is heterogeneous and cannot be reduced to HRV, oxytocin or one attachment style.

Publication record
R76SUPPORTED INTERPRETATION

Social Baseline Theory: the social regulation of risk and effort

Coan JA, Sbarra DA

Claim boundary: Social buffering is heterogeneous and cannot be reduced to HRV, oxytocin or one attachment style.

Publication record
R77SUPPORTED INTERPRETATION

Health neuroscience 2.0: integration with social, cognitive and affective neuroscience

Inagaki TK

Claim boundary: Social buffering is heterogeneous and cannot be reduced to HRV, oxytocin or one attachment style.

Publication record
R78SUPPORTED INTERPRETATION

The Microbiota-Gut-Brain Axis

Cryan JF et al

Claim boundary: Social buffering is heterogeneous and cannot be reduced to HRV, oxytocin or one attachment style.

Publication record
R79SUPPORTED INTERPRETATION

The Gut-Brain Axis

Mayer EA, Nance K, Chen S

Claim boundary: Social buffering is heterogeneous and cannot be reduced to HRV, oxytocin or one attachment style.

Publication record
R80SUPPORTED INTERPRETATION

The Vagus Nerve at the Interface of the Microbiota-Gut-Brain Axis

Bonaz B, Bazin T, Pellissier S

Claim boundary: Social buffering is heterogeneous and cannot be reduced to HRV, oxytocin or one attachment style.

Publication record
C36

EMPIRICAL RESULT · established_research · LECTURE PAGE 52

Moving together is not the same as regulating well together.

What the map supports

Moving together is not the same as regulating well together.

Return to the public explanation

Inference boundary

Synchrony is descriptive unless experimental design identifies direction, mechanism and functional consequence.

Status and counterevidence

established_researchR74-R77

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

4 linked sources — open details
R74EMPIRICAL RESULT

Interactive synchrony and infants’ vagal tone as an index of emotion regulation

Puglisi N et al

Claim boundary: Synchrony is descriptive unless experimental design identifies direction, mechanism and functional consequence.

Publication record
R75EMPIRICAL RESULT

A Developmental Framework of Interpersonal Neural Synchrony

Hoehl S et al

Claim boundary: Synchrony is descriptive unless experimental design identifies direction, mechanism and functional consequence.

Publication record
R76EMPIRICAL RESULT

Social Baseline Theory: the social regulation of risk and effort

Coan JA, Sbarra DA

Claim boundary: Synchrony is descriptive unless experimental design identifies direction, mechanism and functional consequence.

Publication record
R77EMPIRICAL RESULT

Health neuroscience 2.0: integration with social, cognitive and affective neuroscience

Inagaki TK

Claim boundary: Synchrony is descriptive unless experimental design identifies direction, mechanism and functional consequence.

Publication record
C37

EMPIRICAL RESULT · established_research · LECTURE PAGE 54

The gut matters because it is part of the body’s sensing architecture, not because it is a second brain with a single message.

What the map supports

The gut matters because it is part of the body’s sensing architecture, not because it is a second brain with a single message.

Return to the public explanation

Inference boundary

Mechanistic animal findings require careful translation to human subjective experience and psychiatric outcomes.

Status and counterevidence

established_researchR78-R90

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

13 linked sources — open details
R78EMPIRICAL RESULT

The Microbiota-Gut-Brain Axis

Cryan JF et al

Claim boundary: Mechanistic animal findings require careful translation to human subjective experience and psychiatric outcomes.

Publication record
R79EMPIRICAL RESULT

The Gut-Brain Axis

Mayer EA, Nance K, Chen S

Claim boundary: Mechanistic animal findings require careful translation to human subjective experience and psychiatric outcomes.

Publication record
R80EMPIRICAL RESULT

The Vagus Nerve at the Interface of the Microbiota-Gut-Brain Axis

Bonaz B, Bazin T, Pellissier S

Claim boundary: Mechanistic animal findings require careful translation to human subjective experience and psychiatric outcomes.

Publication record
R81EMPIRICAL RESULT

Immunoception: the insular cortex perspective

Rolls A

Claim boundary: Mechanistic animal findings require careful translation to human subjective experience and psychiatric outcomes.

Publication record
R82EMPIRICAL RESULT

The neuroimmune connectome in health and disease

Wheeler MA, Quintana FJ

Claim boundary: Mechanistic animal findings require careful translation to human subjective experience and psychiatric outcomes.

Publication record
R83EMPIRICAL RESULT

Neural representation of cytokines by vagal sensory neurons

Huerta T et al

Claim boundary: Mechanistic animal findings require careful translation to human subjective experience and psychiatric outcomes.

Publication record
R84EMPIRICAL RESULT

Stress-sensitive neural circuits change the gut microbiome via duodenal glands

Chang H et al

Claim boundary: Mechanistic animal findings require careful translation to human subjective experience and psychiatric outcomes.

Publication record
R85EMPIRICAL RESULT

Select microbial metabolites in the small intestinal lumen regulate vagal activity via receptor-mediated signaling

Jameson KG et al

Claim boundary: Mechanistic animal findings require careful translation to human subjective experience and psychiatric outcomes.

Publication record
R86EMPIRICAL RESULT

PIEZO2 in somatosensory neurons controls gastrointestinal transit

Servin-Vences MR et al

Claim boundary: Mechanistic animal findings require careful translation to human subjective experience and psychiatric outcomes.

Publication record
R87EMPIRICAL RESULT

Enteroendocrine cell regulation of the gut-brain axis

Barton JR et al

Claim boundary: Mechanistic animal findings require careful translation to human subjective experience and psychiatric outcomes.

Publication record
R88EMPIRICAL RESULT

Sensory spinal interoceptive pathways and energy balance regulation

Munzberg H, Berthoud HR, Neuhuber W

Claim boundary: Mechanistic animal findings require careful translation to human subjective experience and psychiatric outcomes.

Publication record
R89EMPIRICAL RESULT

Hepatic interoception in health and disease

Berthoud HR et al

Claim boundary: Mechanistic animal findings require careful translation to human subjective experience and psychiatric outcomes.

Publication record
R90EMPIRICAL RESULT

Psychological interventions for interoception in mental health disorders: a systematic review of randomized controlled trials

Heim N et al

Claim boundary: Mechanistic animal findings require careful translation to human subjective experience and psychiatric outcomes.

Publication record
C38

EMERGING EVIDENCE · experimental_evidence · LECTURE PAGE 55

Immune state can change the geometry of action without becoming the single cause of the mind.

What the map supports

Immune state can change the geometry of action without becoming the single cause of the mind.

Return to the public explanation

Inference boundary

Immune mechanisms explain only subsets of psychiatric symptoms; biomarkers such as CRP are nonspecific and should not be used as stand-alone psychiatric explanations.

Status and counterevidence

experimental_evidenceR20, R82-R87

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

7 linked sources — open details
R20EMERGING EVIDENCE

Neural origins of human sickness in interoceptive responses to inflammation

Harrison NA et al

Claim boundary: Immune mechanisms explain only subsets of psychiatric symptoms; biomarkers such as CRP are nonspecific and should not be used as stand-alone psychiatric explanations.

Publication record
R82EMERGING EVIDENCE

The neuroimmune connectome in health and disease

Wheeler MA, Quintana FJ

Claim boundary: Immune mechanisms explain only subsets of psychiatric symptoms; biomarkers such as CRP are nonspecific and should not be used as stand-alone psychiatric explanations.

Publication record
R83EMERGING EVIDENCE

Neural representation of cytokines by vagal sensory neurons

Huerta T et al

Claim boundary: Immune mechanisms explain only subsets of psychiatric symptoms; biomarkers such as CRP are nonspecific and should not be used as stand-alone psychiatric explanations.

Publication record
R84EMERGING EVIDENCE

Stress-sensitive neural circuits change the gut microbiome via duodenal glands

Chang H et al

Claim boundary: Immune mechanisms explain only subsets of psychiatric symptoms; biomarkers such as CRP are nonspecific and should not be used as stand-alone psychiatric explanations.

Publication record
R85EMERGING EVIDENCE

Select microbial metabolites in the small intestinal lumen regulate vagal activity via receptor-mediated signaling

Jameson KG et al

Claim boundary: Immune mechanisms explain only subsets of psychiatric symptoms; biomarkers such as CRP are nonspecific and should not be used as stand-alone psychiatric explanations.

Publication record
R86EMERGING EVIDENCE

PIEZO2 in somatosensory neurons controls gastrointestinal transit

Servin-Vences MR et al

Claim boundary: Immune mechanisms explain only subsets of psychiatric symptoms; biomarkers such as CRP are nonspecific and should not be used as stand-alone psychiatric explanations.

Publication record
R87EMERGING EVIDENCE

Enteroendocrine cell regulation of the gut-brain axis

Barton JR et al

Claim boundary: Immune mechanisms explain only subsets of psychiatric symptoms; biomarkers such as CRP are nonspecific and should not be used as stand-alone psychiatric explanations.

Publication record
C39

SCIENTIFIC GUARDRAIL · negative_controlled_evidence · LECTURE PAGE 56

A whole-body model becomes weaker, not stronger, when every correlation is promoted to a mechanism.

What the map supports

A whole-body model becomes weaker, not stronger, when every correlation is promoted to a mechanism.

Return to the public explanation

Inference boundary

Microbiome associations should be separated from causal intervention evidence, and psychiatric claims require independent replication in humans.

Status and counterevidence

negative_controlled_evidenceR78-R83, R86-R90

Microbiome associations should be separated from causal intervention evidence, and psychiatric claims require independent replication in humans.

11 linked sources — open details
R78SCIENTIFIC GUARDRAIL

The Microbiota-Gut-Brain Axis

Cryan JF et al

Claim boundary: Microbiome associations should be separated from causal intervention evidence, and psychiatric claims require independent replication in humans.

Publication record
R79SCIENTIFIC GUARDRAIL

The Gut-Brain Axis

Mayer EA, Nance K, Chen S

Claim boundary: Microbiome associations should be separated from causal intervention evidence, and psychiatric claims require independent replication in humans.

Publication record
R80SCIENTIFIC GUARDRAIL

The Vagus Nerve at the Interface of the Microbiota-Gut-Brain Axis

Bonaz B, Bazin T, Pellissier S

Claim boundary: Microbiome associations should be separated from causal intervention evidence, and psychiatric claims require independent replication in humans.

Publication record
R81SCIENTIFIC GUARDRAIL

Immunoception: the insular cortex perspective

Rolls A

Claim boundary: Microbiome associations should be separated from causal intervention evidence, and psychiatric claims require independent replication in humans.

Publication record
R82SCIENTIFIC GUARDRAIL

The neuroimmune connectome in health and disease

Wheeler MA, Quintana FJ

Claim boundary: Microbiome associations should be separated from causal intervention evidence, and psychiatric claims require independent replication in humans.

Publication record
R83SCIENTIFIC GUARDRAIL

Neural representation of cytokines by vagal sensory neurons

Huerta T et al

Claim boundary: Microbiome associations should be separated from causal intervention evidence, and psychiatric claims require independent replication in humans.

Publication record
R86SCIENTIFIC GUARDRAIL

PIEZO2 in somatosensory neurons controls gastrointestinal transit

Servin-Vences MR et al

Claim boundary: Microbiome associations should be separated from causal intervention evidence, and psychiatric claims require independent replication in humans.

Publication record
R87SCIENTIFIC GUARDRAIL

Enteroendocrine cell regulation of the gut-brain axis

Barton JR et al

Claim boundary: Microbiome associations should be separated from causal intervention evidence, and psychiatric claims require independent replication in humans.

Publication record
R88SCIENTIFIC GUARDRAIL

Sensory spinal interoceptive pathways and energy balance regulation

Munzberg H, Berthoud HR, Neuhuber W

Claim boundary: Microbiome associations should be separated from causal intervention evidence, and psychiatric claims require independent replication in humans.

Publication record
R89SCIENTIFIC GUARDRAIL

Hepatic interoception in health and disease

Berthoud HR et al

Claim boundary: Microbiome associations should be separated from causal intervention evidence, and psychiatric claims require independent replication in humans.

Publication record
R90SCIENTIFIC GUARDRAIL

Psychological interventions for interoception in mental health disorders: a systematic review of randomized controlled trials

Heim N et al

Claim boundary: Microbiome associations should be separated from causal intervention evidence, and psychiatric claims require independent replication in humans.

Publication record
C40

SUPPORTED INTERPRETATION · conditional_evidence · LECTURE PAGE 58

The goal is not to eliminate arousal. It is to make arousal compatible with more than one future.

What the map supports

The goal is not to eliminate arousal. It is to make arousal compatible with more than one future.

Return to the public explanation

Inference boundary

Exposure should be condition-specific and clinically guided where appropriate; deliberately provoking symptoms is not a universal self-help strategy.

Status and counterevidence

conditional_evidenceR42, R91, R94-R95

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

4 linked sources — open details
R42SUPPORTED INTERPRETATION

Common threads: altered interoceptive processes across affective and anxiety disorders

Saltafossi M, Heck D, Kluger DS, Varga S

Claim boundary: Exposure should be condition-specific and clinically guided where appropriate; deliberately provoking symptoms is not a universal self-help strategy.

Publication record
R91SUPPORTED INTERPRETATION

Interoceptive technologies for psychiatric interventions: from diagnosis to clinical applications

Schoeller F et al

Claim boundary: Exposure should be condition-specific and clinically guided where appropriate; deliberately provoking symptoms is not a universal self-help strategy.

Publication record
R94SUPPORTED INTERPRETATION

Transcutaneous auricular vagus nerve stimulation modulates interoceptive prediction-error processing and allostatic regulation

Ventura-Bort C, Weymar M

Claim boundary: Exposure should be condition-specific and clinically guided where appropriate; deliberately provoking symptoms is not a universal self-help strategy.

Publication record
R95SUPPORTED INTERPRETATION

A systematic review of associations between interoception, vagal tone, and emotional regulation

Pinna T, Edwards DJ

Claim boundary: Exposure should be condition-specific and clinically guided where appropriate; deliberately provoking symptoms is not a universal self-help strategy.

Publication record
C41

SUPPORTED INTERPRETATION · conditional_evidence · LECTURE PAGE 59

Regulation training is valuable when it increases flexibility, not when it turns one preferred physiological state into a new obligation.

What the map supports

Regulation training is valuable when it increases flexibility, not when it turns one preferred physiological state into a new obligation.

Return to the public explanation

Inference boundary

Mindfulness, breathwork and HRV interventions vary substantially; adverse effects and contraindications should not be erased by wellness marketing.

Status and counterevidence

conditional_evidenceR91-R96

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

6 linked sources — open details
R91SUPPORTED INTERPRETATION

Interoceptive technologies for psychiatric interventions: from diagnosis to clinical applications

Schoeller F et al

Claim boundary: Mindfulness, breathwork and HRV interventions vary substantially; adverse effects and contraindications should not be erased by wellness marketing.

Publication record
R92SUPPORTED INTERPRETATION

Heart rate variability biofeedback: how and why does it work?

Lehrer PM, Gevirtz R

Claim boundary: Mindfulness, breathwork and HRV interventions vary substantially; adverse effects and contraindications should not be erased by wellness marketing.

Publication record
R93SUPPORTED INTERPRETATION

Real-time fMRI neurofeedback boosts heartbeat perception by modulating insula activation during interoceptive attention

Haruki Y et al

Claim boundary: Mindfulness, breathwork and HRV interventions vary substantially; adverse effects and contraindications should not be erased by wellness marketing.

Publication record
R94SUPPORTED INTERPRETATION

Transcutaneous auricular vagus nerve stimulation modulates interoceptive prediction-error processing and allostatic regulation

Ventura-Bort C, Weymar M

Claim boundary: Mindfulness, breathwork and HRV interventions vary substantially; adverse effects and contraindications should not be erased by wellness marketing.

Publication record
R95SUPPORTED INTERPRETATION

A systematic review of associations between interoception, vagal tone, and emotional regulation

Pinna T, Edwards DJ

Claim boundary: Mindfulness, breathwork and HRV interventions vary substantially; adverse effects and contraindications should not be erased by wellness marketing.

Publication record
R96SUPPORTED INTERPRETATION

Interoception, contemplative practice, and health

Farb NAS et al

Claim boundary: Mindfulness, breathwork and HRV interventions vary substantially; adverse effects and contraindications should not be erased by wellness marketing.

Publication record
C42

EMERGING EVIDENCE · experimental_evidence · LECTURE PAGE 60

A good intervention is not defined by how directly it touches the nervous system, but by whether it restores useful control without creating new rigidity.

What the map supports

A good intervention is not defined by how directly it touches the nervous system, but by whether it restores useful control without creating new rigidity.

Return to the public explanation

Inference boundary

Mechanistic target engagement, symptom benefit, durability and regulatory approval are separate questions and must be reported separately.

Status and counterevidence

experimental_evidenceR91-R95, R100

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

6 linked sources — open details
R91EMERGING EVIDENCE

Interoceptive technologies for psychiatric interventions: from diagnosis to clinical applications

Schoeller F et al

Claim boundary: Mechanistic target engagement, symptom benefit, durability and regulatory approval are separate questions and must be reported separately.

Publication record
R92EMERGING EVIDENCE

Heart rate variability biofeedback: how and why does it work?

Lehrer PM, Gevirtz R

Claim boundary: Mechanistic target engagement, symptom benefit, durability and regulatory approval are separate questions and must be reported separately.

Publication record
R93EMERGING EVIDENCE

Real-time fMRI neurofeedback boosts heartbeat perception by modulating insula activation during interoceptive attention

Haruki Y et al

Claim boundary: Mechanistic target engagement, symptom benefit, durability and regulatory approval are separate questions and must be reported separately.

Publication record
R94EMERGING EVIDENCE

Transcutaneous auricular vagus nerve stimulation modulates interoceptive prediction-error processing and allostatic regulation

Ventura-Bort C, Weymar M

Claim boundary: Mechanistic target engagement, symptom benefit, durability and regulatory approval are separate questions and must be reported separately.

Publication record
R95EMERGING EVIDENCE

A systematic review of associations between interoception, vagal tone, and emotional regulation

Pinna T, Edwards DJ

Claim boundary: Mechanistic target engagement, symptom benefit, durability and regulatory approval are separate questions and must be reported separately.

Publication record
R100EMERGING EVIDENCE

The heart rate discrimination task: estimating accuracy and precision of interoceptive beliefs

Legrand N et al

Claim boundary: Mechanistic target engagement, symptom benefit, durability and regulatory approval are separate questions and must be reported separately.

Publication record
C43

FLOW HIJACKED SYNTHESIS · flow_hijacked_synthesis · LECTURE PAGE 62

Health is not permanent calm. Health is appropriate movement and reliable return.

What the map supports

Health is not permanent calm. Health is appropriate movement and reliable return.

Return to the public explanation

Inference boundary

There is no single physiological pattern that defines psychological regulation across people and contexts.

Status and counterevidence

flow_hijacked_synthesisR15-R18, R21-R24, R91-R96

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

14 linked sources — open details
R15FLOW HIJACKED SYNTHESIS

The functional role of cardiac activity in perception and action

Skora L, Livermore JJA, Roelofs K

Claim boundary: There is no single physiological pattern that defines psychological regulation across people and contexts.

Publication record
R16FLOW HIJACKED SYNTHESIS

Brain-heart interactions: physiology and clinical implications

Silvani A et al

Claim boundary: There is no single physiological pattern that defines psychological regulation across people and contexts.

Publication record
R17FLOW HIJACKED SYNTHESIS

Neural mechanisms of respiratory interoception

Chan PYS, Lee LY, Davenport PW

Claim boundary: There is no single physiological pattern that defines psychological regulation across people and contexts.

Publication record
R18FLOW HIJACKED SYNTHESIS

Cardiogenic control of affective behavioural state

Hsueh B et al

Claim boundary: There is no single physiological pattern that defines psychological regulation across people and contexts.

Publication record
R21FLOW HIJACKED SYNTHESIS

Allostasis: a model of predictive regulation

Sterling P

Claim boundary: There is no single physiological pattern that defines psychological regulation across people and contexts.

Publication record
R22FLOW HIJACKED SYNTHESIS

Stress and the individual: mechanisms leading to disease

McEwen BS, Stellar E

Claim boundary: There is no single physiological pattern that defines psychological regulation across people and contexts.

Publication record
R23FLOW HIJACKED SYNTHESIS

Stress, adaptation, and disease: allostasis and allostatic load

McEwen BS

Claim boundary: There is no single physiological pattern that defines psychological regulation across people and contexts.

Publication record
R24FLOW HIJACKED SYNTHESIS

Uncertainty and stress: why it causes diseases and how it is mastered by the brain

Peters A, McEwen BS, Friston K

Claim boundary: There is no single physiological pattern that defines psychological regulation across people and contexts.

Publication record
R91FLOW HIJACKED SYNTHESIS

Interoceptive technologies for psychiatric interventions: from diagnosis to clinical applications

Schoeller F et al

Claim boundary: There is no single physiological pattern that defines psychological regulation across people and contexts.

Publication record
R92FLOW HIJACKED SYNTHESIS

Heart rate variability biofeedback: how and why does it work?

Lehrer PM, Gevirtz R

Claim boundary: There is no single physiological pattern that defines psychological regulation across people and contexts.

Publication record
R93FLOW HIJACKED SYNTHESIS

Real-time fMRI neurofeedback boosts heartbeat perception by modulating insula activation during interoceptive attention

Haruki Y et al

Claim boundary: There is no single physiological pattern that defines psychological regulation across people and contexts.

Publication record
R94FLOW HIJACKED SYNTHESIS

Transcutaneous auricular vagus nerve stimulation modulates interoceptive prediction-error processing and allostatic regulation

Ventura-Bort C, Weymar M

Claim boundary: There is no single physiological pattern that defines psychological regulation across people and contexts.

Publication record
R95FLOW HIJACKED SYNTHESIS

A systematic review of associations between interoception, vagal tone, and emotional regulation

Pinna T, Edwards DJ

Claim boundary: There is no single physiological pattern that defines psychological regulation across people and contexts.

Publication record
R96FLOW HIJACKED SYNTHESIS

Interoception, contemplative practice, and health

Farb NAS et al

Claim boundary: There is no single physiological pattern that defines psychological regulation across people and contexts.

Publication record
C44

SCIENTIFIC GUARDRAIL · negative_controlled_evidence · LECTURE PAGE 63

A physiological metric becomes misleading when it is asked to answer a psychological question it was never designed to answer.

What the map supports

A physiological metric becomes misleading when it is asked to answer a psychological question it was never designed to answer.

Return to the public explanation

Inference boundary

The lecture does not use polyvagal categories as established diagnostic states and does not infer felt safety directly from HRV.

Status and counterevidence

negative_controlled_evidenceR09-R18, R73-R76, R93

The lecture does not use polyvagal categories as established diagnostic states and does not infer felt safety directly from HRV.

15 linked sources — open details
R09SCIENTIFIC GUARDRAIL

The Coding Logic of Interoception

Wang R, Chang RB

Claim boundary: The lecture does not use polyvagal categories as established diagnostic states and does not infer felt safety directly from HRV.

Publication record
R10SCIENTIFIC GUARDRAIL

Brain-body physiology: local, reflex, and central communication

Sammons M et al

Claim boundary: The lecture does not use polyvagal categories as established diagnostic states and does not infer felt safety directly from HRV.

Publication record
R11SCIENTIFIC GUARDRAIL

The Organization of the Primate Insular Cortex

Evrard HC

Claim boundary: The lecture does not use polyvagal categories as established diagnostic states and does not infer felt safety directly from HRV.

Publication record
R12SCIENTIFIC GUARDRAIL

Saliency, switching, attention and control: a network model of insula function

Menon V, Uddin LQ

Claim boundary: The lecture does not use polyvagal categories as established diagnostic states and does not infer felt safety directly from HRV.

Publication record
R13SCIENTIFIC GUARDRAIL

Interoceptive rhythms in the brain

Engelen T, Solca M, Tallon-Baudry C

Claim boundary: The lecture does not use polyvagal categories as established diagnostic states and does not infer felt safety directly from HRV.

Publication record
R14SCIENTIFIC GUARDRAIL

Physiological feelings

Pace-Schott EF et al

Claim boundary: The lecture does not use polyvagal categories as established diagnostic states and does not infer felt safety directly from HRV.

Publication record
R15SCIENTIFIC GUARDRAIL

The functional role of cardiac activity in perception and action

Skora L, Livermore JJA, Roelofs K

Claim boundary: The lecture does not use polyvagal categories as established diagnostic states and does not infer felt safety directly from HRV.

Publication record
R16SCIENTIFIC GUARDRAIL

Brain-heart interactions: physiology and clinical implications

Silvani A et al

Claim boundary: The lecture does not use polyvagal categories as established diagnostic states and does not infer felt safety directly from HRV.

Publication record
R17SCIENTIFIC GUARDRAIL

Neural mechanisms of respiratory interoception

Chan PYS, Lee LY, Davenport PW

Claim boundary: The lecture does not use polyvagal categories as established diagnostic states and does not infer felt safety directly from HRV.

Publication record
R18SCIENTIFIC GUARDRAIL

Cardiogenic control of affective behavioural state

Hsueh B et al

Claim boundary: The lecture does not use polyvagal categories as established diagnostic states and does not infer felt safety directly from HRV.

Publication record
R73SCIENTIFIC GUARDRAIL

Keep Calm and Cuddle On: social touch as a stress buffer

Morrison I

Claim boundary: The lecture does not use polyvagal categories as established diagnostic states and does not infer felt safety directly from HRV.

Publication record
R74SCIENTIFIC GUARDRAIL

Interactive synchrony and infants’ vagal tone as an index of emotion regulation

Puglisi N et al

Claim boundary: The lecture does not use polyvagal categories as established diagnostic states and does not infer felt safety directly from HRV.

Publication record
R75SCIENTIFIC GUARDRAIL

A Developmental Framework of Interpersonal Neural Synchrony

Hoehl S et al

Claim boundary: The lecture does not use polyvagal categories as established diagnostic states and does not infer felt safety directly from HRV.

Publication record
R76SCIENTIFIC GUARDRAIL

Social Baseline Theory: the social regulation of risk and effort

Coan JA, Sbarra DA

Claim boundary: The lecture does not use polyvagal categories as established diagnostic states and does not infer felt safety directly from HRV.

Publication record
R93SCIENTIFIC GUARDRAIL

Real-time fMRI neurofeedback boosts heartbeat perception by modulating insula activation during interoceptive attention

Haruki Y et al

Claim boundary: The lecture does not use polyvagal categories as established diagnostic states and does not infer felt safety directly from HRV.

Publication record
C45

SCIENTIFIC GUARDRAIL · negative_controlled_evidence · LECTURE PAGE 64

The body can carry history as altered dynamics without storing the past as a hidden object.

What the map supports

The body can carry history as altered dynamics without storing the past as a hidden object.

Return to the public explanation

Inference boundary

Persistent bodily consequences of trauma are real; the caution concerns literalized storage claims, not the legitimacy of embodied symptoms.

Status and counterevidence

negative_controlled_evidenceR50-R52, R67-R77

Persistent bodily consequences of trauma are real; the caution concerns literalized storage claims, not the legitimacy of embodied symptoms.

14 linked sources — open details
R50SCIENTIFIC GUARDRAIL

A roadmap to understanding interoceptive awareness and post-traumatic stress disorder: a scoping review

Leech K, Stapleton P, Patching A

Claim boundary: Persistent bodily consequences of trauma are real; the caution concerns literalized storage claims, not the legitimacy of embodied symptoms.

Publication record
R51SCIENTIFIC GUARDRAIL

The brain-body disconnect: a somatic sensory basis for trauma-related disorders

Kearney BE, Lanius RA

Claim boundary: Persistent bodily consequences of trauma are real; the caution concerns literalized storage claims, not the legitimacy of embodied symptoms.

Publication record
R52SCIENTIFIC GUARDRAIL

How processing of internal and external sensory information shapes engagement with the world after trauma

Harricharan S, McKinnon MC, Lanius RA

Claim boundary: Persistent bodily consequences of trauma are real; the caution concerns literalized storage claims, not the legitimacy of embodied symptoms.

Publication record
R67SCIENTIFIC GUARDRAIL

Interoception and psychopathology: a developmental neuroscience perspective

Murphy J, Brewer R, Catmur C, Bird G

Claim boundary: Persistent bodily consequences of trauma are real; the caution concerns literalized storage claims, not the legitimacy of embodied symptoms.

Publication record
R68SCIENTIFIC GUARDRAIL

Being in Tune With Your Body: the emergence of interoceptive processing through caregiver-infant feeding interactions

Filippetti ML

Claim boundary: Persistent bodily consequences of trauma are real; the caution concerns literalized storage claims, not the legitimacy of embodied symptoms.

Publication record
R69SCIENTIFIC GUARDRAIL

The body comes first: embodied reparation and the co-creation of infant bodily-self

Montirosso R, McGlone F

Claim boundary: Persistent bodily consequences of trauma are real; the caution concerns literalized storage claims, not the legitimacy of embodied symptoms.

Publication record
R70SCIENTIFIC GUARDRAIL

Affective regulation through touch: homeostatic and allostatic mechanisms

Fotopoulou A, von Mohr M, Krahe C

Claim boundary: Persistent bodily consequences of trauma are real; the caution concerns literalized storage claims, not the legitimacy of embodied symptoms.

Publication record
R71SCIENTIFIC GUARDRAIL

Developmental perspectives on interpersonal affective touch

Crucianelli L, Filippetti ML

Claim boundary: Persistent bodily consequences of trauma are real; the caution concerns literalized storage claims, not the legitimacy of embodied symptoms.

Publication record
R72SCIENTIFIC GUARDRAIL

What are C-tactile afferents and how do they relate to affective touch?

Schirmer A, Croy I, Ackerley R

Claim boundary: Persistent bodily consequences of trauma are real; the caution concerns literalized storage claims, not the legitimacy of embodied symptoms.

Publication record
R73SCIENTIFIC GUARDRAIL

Keep Calm and Cuddle On: social touch as a stress buffer

Morrison I

Claim boundary: Persistent bodily consequences of trauma are real; the caution concerns literalized storage claims, not the legitimacy of embodied symptoms.

Publication record
R74SCIENTIFIC GUARDRAIL

Interactive synchrony and infants’ vagal tone as an index of emotion regulation

Puglisi N et al

Claim boundary: Persistent bodily consequences of trauma are real; the caution concerns literalized storage claims, not the legitimacy of embodied symptoms.

Publication record
R75SCIENTIFIC GUARDRAIL

A Developmental Framework of Interpersonal Neural Synchrony

Hoehl S et al

Claim boundary: Persistent bodily consequences of trauma are real; the caution concerns literalized storage claims, not the legitimacy of embodied symptoms.

Publication record
R76SCIENTIFIC GUARDRAIL

Social Baseline Theory: the social regulation of risk and effort

Coan JA, Sbarra DA

Claim boundary: Persistent bodily consequences of trauma are real; the caution concerns literalized storage claims, not the legitimacy of embodied symptoms.

Publication record
R77SCIENTIFIC GUARDRAIL

Health neuroscience 2.0: integration with social, cognitive and affective neuroscience

Inagaki TK

Claim boundary: Persistent bodily consequences of trauma are real; the caution concerns literalized storage claims, not the legitimacy of embodied symptoms.

Publication record
C46

NEW HYPOTHESIS · flow_hijacked_synthesis · LECTURE PAGE 66

Capture begins when a prediction does not merely interpret the state but helps recreate the state that makes the prediction look right.

What the map supports

Capture begins when a prediction does not merely interpret the state but helps recreate the state that makes the prediction look right.

Return to the public explanation

Inference boundary

Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Status and counterevidence

original Flow Hijacked theoretical synthesis and falsifiable hypothesis; not an established scientific mechanismR25-R40, R41-R66

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

42 linked sources — open details
R25NEW HYPOTHESIS

Active inference, homeostatic regulation and adaptive behavioural control

Pezzulo G, Rigoli F, Friston K

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R26NEW HYPOTHESIS

Active interoceptive inference and the emotional brain

Seth AK, Friston KJ

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R27NEW HYPOTHESIS

Interoceptive predictions in the brain

Barrett LF, Simmons WK

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R28NEW HYPOTHESIS

The theory of constructed emotion: an active inference account of interoception and categorization

Barrett LF

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R29NEW HYPOTHESIS

Interoceptive inference: from computational neuroscience to clinic

Owens AP, Allen M, Ondobaka S, Friston K

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R30NEW HYPOTHESIS

An Active Inference Approach to Interoceptive Psychopathology

Paulus MP, Feinstein JS, Khalsa SS

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R31NEW HYPOTHESIS

Computational psychosomatics and computational psychiatry: toward a joint framework for differential diagnosis

Petzschner FH, Weber LAE, Gard T, Stephan KE

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R32NEW HYPOTHESIS

Allostatic Self-efficacy: a metacognitive theory of dyshomeostasis-induced fatigue and depression

Stephan KE et al

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R33NEW HYPOTHESIS

A Bayesian computational model reveals a failure to adapt interoceptive precision estimates across depression, anxiety, eating, and substance use disorders

Smith R et al

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R34NEW HYPOTHESIS

Transdiagnostic failure to adapt interoceptive precision estimates across affective, substance use, and eating disorders: replication and extension

Lavalley CA et al

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R35NEW HYPOTHESIS

Allostatic interoceptive overload across psychiatric and neurological conditions

Santamaria-Garcia H et al

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R36NEW HYPOTHESIS

In the Body’s Eye: the computational anatomy of interoceptive inference

Allen M, Levy AR, Parr T, Friston K

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R37NEW HYPOTHESIS

Interoception as modeling, allostasis as control

Sennesh E et al

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R38NEW HYPOTHESIS

Allostasis as a core feature of hierarchical gradients in the human brain

Katsumi Y et al

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R39NEW HYPOTHESIS

Intrinsic timescales and predictive allostatic interoception in brain health and disease

Ibanez A, Northoff G

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R40NEW HYPOTHESIS

The energetic cost of allostasis and allostatic load

Bobba-Alves N, Juster RP, Picard M

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R41NEW HYPOTHESIS

Atypical interoception as a common risk factor for psychopathology: a review

Brewer R, Murphy J, Bird G

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R42NEW HYPOTHESIS

Common threads: altered interoceptive processes across affective and anxiety disorders

Saltafossi M, Heck D, Kluger DS, Varga S

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R43NEW HYPOTHESIS

Interoception in anxiety, depression, and psychosis: a review

Jenkinson PM, Fotopoulou A, Ibanez A, Rossell SL

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R44NEW HYPOTHESIS

Major depressive disorder is associated with impaired interoceptive accuracy: a systematic review

Eggart M et al

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R45NEW HYPOTHESIS

Interoceptive Processing in Substance Use Disorders: from neuroanatomy to computational models and predictive coding

Paulus MP

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R46NEW HYPOTHESIS

A Systematic Review of Interoception in Substance Use Disorders

Im JJ et al

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R47NEW HYPOTHESIS

Gastrointestinal Interoception in Eating Disorders: Charting a New Path

Khalsa SS, Berner LA, Anderson LM

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R48NEW HYPOTHESIS

Interoception and Obsessive-Compulsive Disorder: a review of current evidence and future directions

Bragdon LB et al

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R49NEW HYPOTHESIS

Interoception abnormalities in schizophrenia: review and integration with Bayesian accounts of psychosis

Yao B, Thakkar KN

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R50NEW HYPOTHESIS

A roadmap to understanding interoceptive awareness and post-traumatic stress disorder: a scoping review

Leech K, Stapleton P, Patching A

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R51NEW HYPOTHESIS

The brain-body disconnect: a somatic sensory basis for trauma-related disorders

Kearney BE, Lanius RA

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R52NEW HYPOTHESIS

How processing of internal and external sensory information shapes engagement with the world after trauma

Harricharan S, McKinnon MC, Lanius RA

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R53NEW HYPOTHESIS

Perceptual insensitivity to the modulation of interoceptive signals in depression, anxiety, and substance use disorders

Smith R et al

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R54NEW HYPOTHESIS

Cardiac interoception in patients accessing secondary mental health services: a transdiagnostic study

Critchley HD et al

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R55NEW HYPOTHESIS

Insular dysfunction of interoception in major depressive disorder: a neuroimaging perspective

Hu L et al

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R56NEW HYPOTHESIS

Insula-cerebellar functional connectivity associated with somatic symptoms in mood disorders

Hattori S et al

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R57NEW HYPOTHESIS

Interoceptive ability is uncorrelated across respiratory and cardiac axes in a large-scale psychophysical study

Banellis L et al

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R58NEW HYPOTHESIS

Functional neurological disorder: new subtypes and shared mechanisms

Hallett M et al

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R59NEW HYPOTHESIS

Persistent physical symptoms: definition, genesis, and management

Lowe B et al

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R60NEW HYPOTHESIS

Persistent Physical Symptoms as Perceptual Dysregulation: a neuropsychobehavioral model and clinical implications

Henningsen P et al

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R61NEW HYPOTHESIS

Effect of Pain Reprocessing Therapy vs Placebo and Usual Care for Patients With Chronic Back Pain

Ashar YK et al

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R62NEW HYPOTHESIS

Shape shifting pain: chronification of back pain shifts brain representation

Hashmi JA et al

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R63NEW HYPOTHESIS

Reward deficiency and anti-reward in pain chronification

Borsook D et al

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R64NEW HYPOTHESIS

Beyond the symptom: the biology of fatigue

Raizen DM et al

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R65NEW HYPOTHESIS

Neurobiology of eating behavior, nutrition, and health

Stover PJ et al

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
R66NEW HYPOTHESIS

Heterogeneous appetite patterns in depression: computational modeling of nutritional interoception, reward processing, and decision-making

Uchida Y et al

Claim boundary: Interoceptive Attractor Capture is a proposed Flow Hijacked model. Attractor depth, basin geometry and precision rigidity have not been directly measured as a unified clinical construct.

Publication record
C47

NEW HYPOTHESIS · flow_hijacked_synthesis · LECTURE PAGE 67

The central pathology is not a bad state. It is the shrinking number of ways to leave it.

What the map supports

The central pathology is not a bad state. It is the shrinking number of ways to leave it.

Return to the public explanation

Inference boundary

Policy entropy and hysteresis are formal hypotheses. They require operational definitions and longitudinal perturbation data before clinical use.

Status and counterevidence

original Flow Hijacked theoretical synthesis and falsifiable hypothesis; not an established scientific mechanismR33-R40, R45-R66

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

30 linked sources — open details
R33NEW HYPOTHESIS

A Bayesian computational model reveals a failure to adapt interoceptive precision estimates across depression, anxiety, eating, and substance use disorders

Smith R et al

Claim boundary: Policy entropy and hysteresis are formal hypotheses. They require operational definitions and longitudinal perturbation data before clinical use.

Publication record
R34NEW HYPOTHESIS

Transdiagnostic failure to adapt interoceptive precision estimates across affective, substance use, and eating disorders: replication and extension

Lavalley CA et al

Claim boundary: Policy entropy and hysteresis are formal hypotheses. They require operational definitions and longitudinal perturbation data before clinical use.

Publication record
R35NEW HYPOTHESIS

Allostatic interoceptive overload across psychiatric and neurological conditions

Santamaria-Garcia H et al

Claim boundary: Policy entropy and hysteresis are formal hypotheses. They require operational definitions and longitudinal perturbation data before clinical use.

Publication record
R36NEW HYPOTHESIS

In the Body’s Eye: the computational anatomy of interoceptive inference

Allen M, Levy AR, Parr T, Friston K

Claim boundary: Policy entropy and hysteresis are formal hypotheses. They require operational definitions and longitudinal perturbation data before clinical use.

Publication record
R37NEW HYPOTHESIS

Interoception as modeling, allostasis as control

Sennesh E et al

Claim boundary: Policy entropy and hysteresis are formal hypotheses. They require operational definitions and longitudinal perturbation data before clinical use.

Publication record
R38NEW HYPOTHESIS

Allostasis as a core feature of hierarchical gradients in the human brain

Katsumi Y et al

Claim boundary: Policy entropy and hysteresis are formal hypotheses. They require operational definitions and longitudinal perturbation data before clinical use.

Publication record
R39NEW HYPOTHESIS

Intrinsic timescales and predictive allostatic interoception in brain health and disease

Ibanez A, Northoff G

Claim boundary: Policy entropy and hysteresis are formal hypotheses. They require operational definitions and longitudinal perturbation data before clinical use.

Publication record
R40NEW HYPOTHESIS

The energetic cost of allostasis and allostatic load

Bobba-Alves N, Juster RP, Picard M

Claim boundary: Policy entropy and hysteresis are formal hypotheses. They require operational definitions and longitudinal perturbation data before clinical use.

Publication record
R45NEW HYPOTHESIS

Interoceptive Processing in Substance Use Disorders: from neuroanatomy to computational models and predictive coding

Paulus MP

Claim boundary: Policy entropy and hysteresis are formal hypotheses. They require operational definitions and longitudinal perturbation data before clinical use.

Publication record
R46NEW HYPOTHESIS

A Systematic Review of Interoception in Substance Use Disorders

Im JJ et al

Claim boundary: Policy entropy and hysteresis are formal hypotheses. They require operational definitions and longitudinal perturbation data before clinical use.

Publication record
R47NEW HYPOTHESIS

Gastrointestinal Interoception in Eating Disorders: Charting a New Path

Khalsa SS, Berner LA, Anderson LM

Claim boundary: Policy entropy and hysteresis are formal hypotheses. They require operational definitions and longitudinal perturbation data before clinical use.

Publication record
R48NEW HYPOTHESIS

Interoception and Obsessive-Compulsive Disorder: a review of current evidence and future directions

Bragdon LB et al

Claim boundary: Policy entropy and hysteresis are formal hypotheses. They require operational definitions and longitudinal perturbation data before clinical use.

Publication record
R49NEW HYPOTHESIS

Interoception abnormalities in schizophrenia: review and integration with Bayesian accounts of psychosis

Yao B, Thakkar KN

Claim boundary: Policy entropy and hysteresis are formal hypotheses. They require operational definitions and longitudinal perturbation data before clinical use.

Publication record
R50NEW HYPOTHESIS

A roadmap to understanding interoceptive awareness and post-traumatic stress disorder: a scoping review

Leech K, Stapleton P, Patching A

Claim boundary: Policy entropy and hysteresis are formal hypotheses. They require operational definitions and longitudinal perturbation data before clinical use.

Publication record
R51NEW HYPOTHESIS

The brain-body disconnect: a somatic sensory basis for trauma-related disorders

Kearney BE, Lanius RA

Claim boundary: Policy entropy and hysteresis are formal hypotheses. They require operational definitions and longitudinal perturbation data before clinical use.

Publication record
R52NEW HYPOTHESIS

How processing of internal and external sensory information shapes engagement with the world after trauma

Harricharan S, McKinnon MC, Lanius RA

Claim boundary: Policy entropy and hysteresis are formal hypotheses. They require operational definitions and longitudinal perturbation data before clinical use.

Publication record
R53NEW HYPOTHESIS

Perceptual insensitivity to the modulation of interoceptive signals in depression, anxiety, and substance use disorders

Smith R et al

Claim boundary: Policy entropy and hysteresis are formal hypotheses. They require operational definitions and longitudinal perturbation data before clinical use.

Publication record
R54NEW HYPOTHESIS

Cardiac interoception in patients accessing secondary mental health services: a transdiagnostic study

Critchley HD et al

Claim boundary: Policy entropy and hysteresis are formal hypotheses. They require operational definitions and longitudinal perturbation data before clinical use.

Publication record
R55NEW HYPOTHESIS

Insular dysfunction of interoception in major depressive disorder: a neuroimaging perspective

Hu L et al

Claim boundary: Policy entropy and hysteresis are formal hypotheses. They require operational definitions and longitudinal perturbation data before clinical use.

Publication record
R56NEW HYPOTHESIS

Insula-cerebellar functional connectivity associated with somatic symptoms in mood disorders

Hattori S et al

Claim boundary: Policy entropy and hysteresis are formal hypotheses. They require operational definitions and longitudinal perturbation data before clinical use.

Publication record
R57NEW HYPOTHESIS

Interoceptive ability is uncorrelated across respiratory and cardiac axes in a large-scale psychophysical study

Banellis L et al

Claim boundary: Policy entropy and hysteresis are formal hypotheses. They require operational definitions and longitudinal perturbation data before clinical use.

Publication record
R58NEW HYPOTHESIS

Functional neurological disorder: new subtypes and shared mechanisms

Hallett M et al

Claim boundary: Policy entropy and hysteresis are formal hypotheses. They require operational definitions and longitudinal perturbation data before clinical use.

Publication record
R59NEW HYPOTHESIS

Persistent physical symptoms: definition, genesis, and management

Lowe B et al

Claim boundary: Policy entropy and hysteresis are formal hypotheses. They require operational definitions and longitudinal perturbation data before clinical use.

Publication record
R60NEW HYPOTHESIS

Persistent Physical Symptoms as Perceptual Dysregulation: a neuropsychobehavioral model and clinical implications

Henningsen P et al

Claim boundary: Policy entropy and hysteresis are formal hypotheses. They require operational definitions and longitudinal perturbation data before clinical use.

Publication record
R61NEW HYPOTHESIS

Effect of Pain Reprocessing Therapy vs Placebo and Usual Care for Patients With Chronic Back Pain

Ashar YK et al

Claim boundary: Policy entropy and hysteresis are formal hypotheses. They require operational definitions and longitudinal perturbation data before clinical use.

Publication record
R62NEW HYPOTHESIS

Shape shifting pain: chronification of back pain shifts brain representation

Hashmi JA et al

Claim boundary: Policy entropy and hysteresis are formal hypotheses. They require operational definitions and longitudinal perturbation data before clinical use.

Publication record
R63NEW HYPOTHESIS

Reward deficiency and anti-reward in pain chronification

Borsook D et al

Claim boundary: Policy entropy and hysteresis are formal hypotheses. They require operational definitions and longitudinal perturbation data before clinical use.

Publication record
R64NEW HYPOTHESIS

Beyond the symptom: the biology of fatigue

Raizen DM et al

Claim boundary: Policy entropy and hysteresis are formal hypotheses. They require operational definitions and longitudinal perturbation data before clinical use.

Publication record
R65NEW HYPOTHESIS

Neurobiology of eating behavior, nutrition, and health

Stover PJ et al

Claim boundary: Policy entropy and hysteresis are formal hypotheses. They require operational definitions and longitudinal perturbation data before clinical use.

Publication record
R66NEW HYPOTHESIS

Heterogeneous appetite patterns in depression: computational modeling of nutritional interoception, reward processing, and decision-making

Uchida Y et al

Claim boundary: Policy entropy and hysteresis are formal hypotheses. They require operational definitions and longitudinal perturbation data before clinical use.

Publication record
C48

NEW HYPOTHESIS · flow_hijacked_synthesis · LECTURE PAGE 68

Recovery is not simply leaving a bad state. It is regaining somewhere else to go.

What the map supports

Recovery is not simply leaving a bad state. It is regaining somewhere else to go.

Return to the public explanation

Inference boundary

The proposed measures are a research program, not established clinical endpoints. Failure to outperform simpler models should lead to revision or rejection of the concept.

Status and counterevidence

original Flow Hijacked theoretical synthesis and falsifiable hypothesis; not an established scientific mechanismR33-R40, R91-R100

No separate counterevidence was recorded in the canonical section; the inference boundary still applies.

18 linked sources — open details
R33NEW HYPOTHESIS

A Bayesian computational model reveals a failure to adapt interoceptive precision estimates across depression, anxiety, eating, and substance use disorders

Smith R et al

Claim boundary: The proposed measures are a research program, not established clinical endpoints. Failure to outperform simpler models should lead to revision or rejection of the concept.

Publication record
R34NEW HYPOTHESIS

Transdiagnostic failure to adapt interoceptive precision estimates across affective, substance use, and eating disorders: replication and extension

Lavalley CA et al

Claim boundary: The proposed measures are a research program, not established clinical endpoints. Failure to outperform simpler models should lead to revision or rejection of the concept.

Publication record
R35NEW HYPOTHESIS

Allostatic interoceptive overload across psychiatric and neurological conditions

Santamaria-Garcia H et al

Claim boundary: The proposed measures are a research program, not established clinical endpoints. Failure to outperform simpler models should lead to revision or rejection of the concept.

Publication record
R36NEW HYPOTHESIS

In the Body’s Eye: the computational anatomy of interoceptive inference

Allen M, Levy AR, Parr T, Friston K

Claim boundary: The proposed measures are a research program, not established clinical endpoints. Failure to outperform simpler models should lead to revision or rejection of the concept.

Publication record
R37NEW HYPOTHESIS

Interoception as modeling, allostasis as control

Sennesh E et al

Claim boundary: The proposed measures are a research program, not established clinical endpoints. Failure to outperform simpler models should lead to revision or rejection of the concept.

Publication record
R38NEW HYPOTHESIS

Allostasis as a core feature of hierarchical gradients in the human brain

Katsumi Y et al

Claim boundary: The proposed measures are a research program, not established clinical endpoints. Failure to outperform simpler models should lead to revision or rejection of the concept.

Publication record
R39NEW HYPOTHESIS

Intrinsic timescales and predictive allostatic interoception in brain health and disease

Ibanez A, Northoff G

Claim boundary: The proposed measures are a research program, not established clinical endpoints. Failure to outperform simpler models should lead to revision or rejection of the concept.

Publication record
R40NEW HYPOTHESIS

The energetic cost of allostasis and allostatic load

Bobba-Alves N, Juster RP, Picard M

Claim boundary: The proposed measures are a research program, not established clinical endpoints. Failure to outperform simpler models should lead to revision or rejection of the concept.

Publication record
R91NEW HYPOTHESIS

Interoceptive technologies for psychiatric interventions: from diagnosis to clinical applications

Schoeller F et al

Claim boundary: The proposed measures are a research program, not established clinical endpoints. Failure to outperform simpler models should lead to revision or rejection of the concept.

Publication record
R92NEW HYPOTHESIS

Heart rate variability biofeedback: how and why does it work?

Lehrer PM, Gevirtz R

Claim boundary: The proposed measures are a research program, not established clinical endpoints. Failure to outperform simpler models should lead to revision or rejection of the concept.

Publication record
R93NEW HYPOTHESIS

Real-time fMRI neurofeedback boosts heartbeat perception by modulating insula activation during interoceptive attention

Haruki Y et al

Claim boundary: The proposed measures are a research program, not established clinical endpoints. Failure to outperform simpler models should lead to revision or rejection of the concept.

Publication record
R94NEW HYPOTHESIS

Transcutaneous auricular vagus nerve stimulation modulates interoceptive prediction-error processing and allostatic regulation

Ventura-Bort C, Weymar M

Claim boundary: The proposed measures are a research program, not established clinical endpoints. Failure to outperform simpler models should lead to revision or rejection of the concept.

Publication record
R95NEW HYPOTHESIS

A systematic review of associations between interoception, vagal tone, and emotional regulation

Pinna T, Edwards DJ

Claim boundary: The proposed measures are a research program, not established clinical endpoints. Failure to outperform simpler models should lead to revision or rejection of the concept.

Publication record
R96NEW HYPOTHESIS

Interoception, contemplative practice, and health

Farb NAS et al

Claim boundary: The proposed measures are a research program, not established clinical endpoints. Failure to outperform simpler models should lead to revision or rejection of the concept.

Publication record
R97NEW HYPOTHESIS

From many to none: meditation and the plasticity of the predictive mind

Laukkonen RE, Slagter HA

Claim boundary: The proposed measures are a research program, not established clinical endpoints. Failure to outperform simpler models should lead to revision or rejection of the concept.

Publication record
R98NEW HYPOTHESIS

Systematic review and meta-analysis of the relationship between heartbeat-evoked potential and interoception

Coll MP et al

Claim boundary: The proposed measures are a research program, not established clinical endpoints. Failure to outperform simpler models should lead to revision or rejection of the concept.

Publication record
R99NEW HYPOTHESIS

The respiratory resistance sensitivity task: quantifying respiratory interoception and metacognition

Nikolova N et al

Claim boundary: The proposed measures are a research program, not established clinical endpoints. Failure to outperform simpler models should lead to revision or rejection of the concept.

Publication record
R100NEW HYPOTHESIS

The heart rate discrimination task: estimating accuracy and precision of interoceptive beliefs

Legrand N et al

Claim boundary: The proposed measures are a research program, not established clinical endpoints. Failure to outperform simpler models should lead to revision or rejection of the concept.

Publication record

FLOW HIJACKED NOVEL CONCEPT

Interoceptive Attractor Capture is a falsifiable hypothesis—not an established scientific mechanism.

This is an original Flow Hijacked theoretical synthesis. It proposes three mutually reinforcing restrictions: Prediction Rigidity, Precision Rigidity and Policy Compression. Hysteresis and basin deepening are bounded formal transfers and analogies, not claims about literal physical energy wells in the brain.

The expression |Ω_accessible| ↓ is a conceptual representation and Flow Hijacked formal hypothesis. It is not a validated clinical biomarker and does not diagnose a person.

UNIFIED SCIENTIFIC CORPUS

100 publications after unifying both bibliographies.

The lecture bibliographies do not supply year, journal, DOI, PMID or a canonical URL. Those fields therefore remain null rather than being invented. Titles, authors, lecture chapters and linked claims are preserved.

R01Interoception and Mental Health: A Roadmap

Khalsa SS et al

BBT-C01 · BBT-C04
R02The Emerging Science of Interoception: Sensing, Integrating, Interpreting, and Regulating Signals within the Self

Chen WG et al

BBT-C01 · BBT-C04
R03How do you feel? Interoception: the sense of the physiological condition of the body

Craig AD

BBT-C01 · BBT-C04
R04Neural systems supporting interoceptive awareness

Critchley HD, Wiens S, Rotshtein P, Ohman A, Dolan RJ

BBT-C01 · BBT-C04
R05Interoception and emotion

Critchley HD, Garfinkel SN

BBT-C01 · BBT-C04 · BBT-C05 · BBT-C19
R06Knowing your own heart: distinguishing interoceptive accuracy from interoceptive awareness

Garfinkel SN et al

BBT-C04 · BBT-C05
R07Towards a comprehensive assessment of interoception in a multi-dimensional framework

Suksasilp C, Garfinkel SN

BBT-C04 · BBT-C05 · BBT-C06
R08The new measures of interoceptive accuracy: a systematic review and assessment

Desmedt O, Luminet O, Walentynowicz M, Corneille O

BBT-C04 · BBT-C05 · BBT-C06
R09The Coding Logic of Interoception

Wang R, Chang RB

BBT-C04 · BBT-C06 · BBT-C07 · BBT-C44
R10Brain-body physiology: local, reflex, and central communication

Sammons M et al

BBT-C01 · BBT-C04 · BBT-C07 · BBT-C08 · BBT-C44
R11The Organization of the Primate Insular Cortex

Evrard HC

BBT-C08 · BBT-C44
R12Saliency, switching, attention and control: a network model of insula function

Menon V, Uddin LQ

BBT-C08 · BBT-C19 · BBT-C44
R13Interoceptive rhythms in the brain

Engelen T, Solca M, Tallon-Baudry C

BBT-C08 · BBT-C09 · BBT-C19 · BBT-C22 · BBT-C24 · BBT-C44
R14Physiological feelings

Pace-Schott EF et al

BBT-C01 · BBT-C04 · BBT-C09 · BBT-C19 · BBT-C22 · BBT-C44
R15The functional role of cardiac activity in perception and action

Skora L, Livermore JJA, Roelofs K

BBT-C01 · BBT-C04 · BBT-C09 · BBT-C22 · BBT-C43 · BBT-C44
R16Brain-heart interactions: physiology and clinical implications

Silvani A et al

BBT-C01 · BBT-C04 · BBT-C09 · BBT-C43 · BBT-C44
R17Neural mechanisms of respiratory interoception

Chan PYS, Lee LY, Davenport PW

BBT-C01 · BBT-C04 · BBT-C08 · BBT-C09 · BBT-C43 · BBT-C44
R18Cardiogenic control of affective behavioural state

Hsueh B et al

BBT-C01 · BBT-C04 · BBT-C09 · BBT-C43 · BBT-C44
R19Fear balance is maintained by bodily feedback to the insular cortex in mice

Klein AS et al

BBT-C04
R20Neural origins of human sickness in interoceptive responses to inflammation

Harrison NA et al

BBT-C04 · BBT-C38
R21Allostasis: a model of predictive regulation

Sterling P

BBT-C02 · BBT-C10 · BBT-C43
R22Stress and the individual: mechanisms leading to disease

McEwen BS, Stellar E

BBT-C02 · BBT-C10 · BBT-C11 · BBT-C25 · BBT-C43
R23Stress, adaptation, and disease: allostasis and allostatic load

McEwen BS

BBT-C02 · BBT-C10 · BBT-C11 · BBT-C24 · BBT-C25 · BBT-C43
R24Uncertainty and stress: why it causes diseases and how it is mastered by the brain

Peters A, McEwen BS, Friston K

BBT-C02 · BBT-C10 · BBT-C11 · BBT-C21 · BBT-C24 · BBT-C25 · BBT-C27 · BBT-C43
R25Active inference, homeostatic regulation and adaptive behavioural control

Pezzulo G, Rigoli F, Friston K

BBT-C02 · BBT-C10 · BBT-C13 · BBT-C15 · BBT-C21 · BBT-C23 · BBT-C27 · BBT-C46
R26Active interoceptive inference and the emotional brain

Seth AK, Friston KJ

BBT-C13 · BBT-C14 · BBT-C15 · BBT-C21 · BBT-C27 · BBT-C46
R27Interoceptive predictions in the brain

Barrett LF, Simmons WK

BBT-C13 · BBT-C14 · BBT-C15 · BBT-C19 · BBT-C21 · BBT-C27 · BBT-C46
R28The theory of constructed emotion: an active inference account of interoception and categorization

Barrett LF

BBT-C13 · BBT-C14 · BBT-C15 · BBT-C19 · BBT-C21 · BBT-C27 · BBT-C46
R29Interoceptive inference: from computational neuroscience to clinic

Owens AP, Allen M, Ondobaka S, Friston K

BBT-C03 · BBT-C13 · BBT-C14 · BBT-C15 · BBT-C21 · BBT-C27 · BBT-C46
R30An Active Inference Approach to Interoceptive Psychopathology

Paulus MP, Feinstein JS, Khalsa SS

BBT-C03 · BBT-C13 · BBT-C14 · BBT-C15 · BBT-C21 · BBT-C27 · BBT-C46
R31Computational psychosomatics and computational psychiatry: toward a joint framework for differential diagnosis

Petzschner FH, Weber LAE, Gard T, Stephan KE

BBT-C03 · BBT-C13 · BBT-C14 · BBT-C15 · BBT-C21 · BBT-C27 · BBT-C46
R32Allostatic Self-efficacy: a metacognitive theory of dyshomeostasis-induced fatigue and depression

Stephan KE et al

BBT-C03 · BBT-C12 · BBT-C14 · BBT-C21 · BBT-C23 · BBT-C29 · BBT-C46
R33A Bayesian computational model reveals a failure to adapt interoceptive precision estimates across depression, anxiety, eating, and substance use disorders

Smith R et al

BBT-C03 · BBT-C14 · BBT-C16 · BBT-C46 · BBT-C47 · BBT-C48
R34Transdiagnostic failure to adapt interoceptive precision estimates across affective, substance use, and eating disorders: replication and extension

Lavalley CA et al

BBT-C03 · BBT-C14 · BBT-C16 · BBT-C18 · BBT-C46 · BBT-C47 · BBT-C48
R35Allostatic interoceptive overload across psychiatric and neurological conditions

Santamaria-Garcia H et al

BBT-C02 · BBT-C03 · BBT-C10 · BBT-C11 · BBT-C24 · BBT-C25 · BBT-C29 · BBT-C46 · BBT-C47 · BBT-C48
R36In the Body’s Eye: the computational anatomy of interoceptive inference

Allen M, Levy AR, Parr T, Friston K

BBT-C03 · BBT-C13 · BBT-C14 · BBT-C46 · BBT-C47 · BBT-C48
R37Interoception as modeling, allostasis as control

Sennesh E et al

BBT-C03 · BBT-C10 · BBT-C13 · BBT-C15 · BBT-C21 · BBT-C23 · BBT-C46 · BBT-C47 · BBT-C48
R38Allostasis as a core feature of hierarchical gradients in the human brain

Katsumi Y et al

BBT-C03 · BBT-C08 · BBT-C10 · BBT-C13 · BBT-C21 · BBT-C46 · BBT-C47 · BBT-C48
R39Intrinsic timescales and predictive allostatic interoception in brain health and disease

Ibanez A, Northoff G

BBT-C03 · BBT-C10 · BBT-C13 · BBT-C21 · BBT-C24 · BBT-C46 · BBT-C47 · BBT-C48
R40The energetic cost of allostasis and allostatic load

Bobba-Alves N, Juster RP, Picard M

BBT-C02 · BBT-C03 · BBT-C10 · BBT-C11 · BBT-C12 · BBT-C21 · BBT-C24 · BBT-C25 · BBT-C46 · BBT-C47 · BBT-C48
R41Atypical interoception as a common risk factor for psychopathology: a review

Brewer R, Murphy J, Bird G

BBT-C03 · BBT-C17 · BBT-C20 · BBT-C27 · BBT-C46
R42Common threads: altered interoceptive processes across affective and anxiety disorders

Saltafossi M, Heck D, Kluger DS, Varga S

BBT-C03 · BBT-C17 · BBT-C27 · BBT-C28 · BBT-C40 · BBT-C46
R43Interoception in anxiety, depression, and psychosis: a review

Jenkinson PM, Fotopoulou A, Ibanez A, Rossell SL

BBT-C03 · BBT-C17 · BBT-C27 · BBT-C28 · BBT-C29 · BBT-C46
R44Major depressive disorder is associated with impaired interoceptive accuracy: a systematic review

Eggart M et al

BBT-C03 · BBT-C17 · BBT-C27 · BBT-C28 · BBT-C29 · BBT-C46
R45Interoceptive Processing in Substance Use Disorders: from neuroanatomy to computational models and predictive coding

Paulus MP

BBT-C03 · BBT-C17 · BBT-C27 · BBT-C29 · BBT-C31 · BBT-C32 · BBT-C33 · BBT-C46 · BBT-C47
R46A Systematic Review of Interoception in Substance Use Disorders

Im JJ et al

BBT-C03 · BBT-C17 · BBT-C27 · BBT-C29 · BBT-C31 · BBT-C32 · BBT-C33 · BBT-C46 · BBT-C47
R47Gastrointestinal Interoception in Eating Disorders: Charting a New Path

Khalsa SS, Berner LA, Anderson LM

BBT-C03 · BBT-C17 · BBT-C27 · BBT-C46 · BBT-C47
R48Interoception and Obsessive-Compulsive Disorder: a review of current evidence and future directions

Bragdon LB et al

BBT-C03 · BBT-C17 · BBT-C27 · BBT-C46 · BBT-C47
R49Interoception abnormalities in schizophrenia: review and integration with Bayesian accounts of psychosis

Yao B, Thakkar KN

BBT-C03 · BBT-C17 · BBT-C20 · BBT-C27 · BBT-C30 · BBT-C46 · BBT-C47
R50A roadmap to understanding interoceptive awareness and post-traumatic stress disorder: a scoping review

Leech K, Stapleton P, Patching A

BBT-C03 · BBT-C17 · BBT-C22 · BBT-C27 · BBT-C30 · BBT-C45 · BBT-C46 · BBT-C47
R51The brain-body disconnect: a somatic sensory basis for trauma-related disorders

Kearney BE, Lanius RA

BBT-C03 · BBT-C17 · BBT-C22 · BBT-C27 · BBT-C30 · BBT-C45 · BBT-C46 · BBT-C47
R52How processing of internal and external sensory information shapes engagement with the world after trauma

Harricharan S, McKinnon MC, Lanius RA

BBT-C03 · BBT-C17 · BBT-C22 · BBT-C25 · BBT-C27 · BBT-C30 · BBT-C45 · BBT-C46 · BBT-C47
R53Perceptual insensitivity to the modulation of interoceptive signals in depression, anxiety, and substance use disorders

Smith R et al

BBT-C03 · BBT-C16 · BBT-C17 · BBT-C27 · BBT-C28 · BBT-C30 · BBT-C46 · BBT-C47
R54Cardiac interoception in patients accessing secondary mental health services: a transdiagnostic study

Critchley HD et al

BBT-C03 · BBT-C05 · BBT-C16 · BBT-C17 · BBT-C27 · BBT-C30 · BBT-C46 · BBT-C47
R55Insular dysfunction of interoception in major depressive disorder: a neuroimaging perspective

Hu L et al

BBT-C03 · BBT-C16 · BBT-C17 · BBT-C27 · BBT-C29 · BBT-C30 · BBT-C46 · BBT-C47
R56Insula-cerebellar functional connectivity associated with somatic symptoms in mood disorders

Hattori S et al

BBT-C03 · BBT-C16 · BBT-C17 · BBT-C27 · BBT-C29 · BBT-C30 · BBT-C46 · BBT-C47
R57Interoceptive ability is uncorrelated across respiratory and cardiac axes in a large-scale psychophysical study

Banellis L et al

BBT-C03 · BBT-C06 · BBT-C16 · BBT-C17 · BBT-C27 · BBT-C30 · BBT-C46 · BBT-C47
R58Functional neurological disorder: new subtypes and shared mechanisms

Hallett M et al

BBT-C03 · BBT-C30 · BBT-C46 · BBT-C47
R59Persistent physical symptoms: definition, genesis, and management

Lowe B et al

BBT-C03 · BBT-C30 · BBT-C46 · BBT-C47
R60Persistent Physical Symptoms as Perceptual Dysregulation: a neuropsychobehavioral model and clinical implications

Henningsen P et al

BBT-C03 · BBT-C30 · BBT-C46 · BBT-C47
R61Effect of Pain Reprocessing Therapy vs Placebo and Usual Care for Patients With Chronic Back Pain

Ashar YK et al

BBT-C03 · BBT-C31 · BBT-C46 · BBT-C47
R62Shape shifting pain: chronification of back pain shifts brain representation

Hashmi JA et al

BBT-C03 · BBT-C31 · BBT-C46 · BBT-C47
R63Reward deficiency and anti-reward in pain chronification

Borsook D et al

BBT-C03 · BBT-C31 · BBT-C32 · BBT-C46 · BBT-C47
R64Beyond the symptom: the biology of fatigue

Raizen DM et al

BBT-C03 · BBT-C12 · BBT-C31 · BBT-C32 · BBT-C46 · BBT-C47
R65Neurobiology of eating behavior, nutrition, and health

Stover PJ et al

BBT-C03 · BBT-C12 · BBT-C23 · BBT-C29 · BBT-C31 · BBT-C32 · BBT-C46 · BBT-C47
R66Heterogeneous appetite patterns in depression: computational modeling of nutritional interoception, reward processing, and decision-making

Uchida Y et al

BBT-C03 · BBT-C12 · BBT-C23 · BBT-C29 · BBT-C31 · BBT-C32 · BBT-C46 · BBT-C47
R67Interoception and psychopathology: a developmental neuroscience perspective

Murphy J, Brewer R, Catmur C, Bird G

BBT-C20 · BBT-C26 · BBT-C34 · BBT-C45
R68Being in Tune With Your Body: the emergence of interoceptive processing through caregiver-infant feeding interactions

Filippetti ML

BBT-C26 · BBT-C34 · BBT-C45
R69The body comes first: embodied reparation and the co-creation of infant bodily-self

Montirosso R, McGlone F

BBT-C26 · BBT-C34 · BBT-C45
R70Affective regulation through touch: homeostatic and allostatic mechanisms

Fotopoulou A, von Mohr M, Krahe C

BBT-C26 · BBT-C34 · BBT-C45
R71Developmental perspectives on interpersonal affective touch

Crucianelli L, Filippetti ML

BBT-C26 · BBT-C34 · BBT-C45
R72What are C-tactile afferents and how do they relate to affective touch?

Schirmer A, Croy I, Ackerley R

BBT-C26 · BBT-C34 · BBT-C35 · BBT-C45
R73Keep Calm and Cuddle On: social touch as a stress buffer

Morrison I

BBT-C26 · BBT-C34 · BBT-C35 · BBT-C44 · BBT-C45
R74Interactive synchrony and infants’ vagal tone as an index of emotion regulation

Puglisi N et al

BBT-C26 · BBT-C34 · BBT-C35 · BBT-C36 · BBT-C44 · BBT-C45
R75A Developmental Framework of Interpersonal Neural Synchrony

Hoehl S et al

BBT-C26 · BBT-C34 · BBT-C35 · BBT-C36 · BBT-C44 · BBT-C45
R76Social Baseline Theory: the social regulation of risk and effort

Coan JA, Sbarra DA

BBT-C26 · BBT-C34 · BBT-C35 · BBT-C36 · BBT-C44 · BBT-C45
R77Health neuroscience 2.0: integration with social, cognitive and affective neuroscience

Inagaki TK

BBT-C26 · BBT-C34 · BBT-C35 · BBT-C36 · BBT-C45
R78The Microbiota-Gut-Brain Axis

Cryan JF et al

BBT-C35 · BBT-C37 · BBT-C39
R79The Gut-Brain Axis

Mayer EA, Nance K, Chen S

BBT-C35 · BBT-C37 · BBT-C39
R80The Vagus Nerve at the Interface of the Microbiota-Gut-Brain Axis

Bonaz B, Bazin T, Pellissier S

BBT-C35 · BBT-C37 · BBT-C39
R81Immunoception: the insular cortex perspective

Rolls A

BBT-C07 · BBT-C37 · BBT-C39
R82The neuroimmune connectome in health and disease

Wheeler MA, Quintana FJ

BBT-C37 · BBT-C38 · BBT-C39
R83Neural representation of cytokines by vagal sensory neurons

Huerta T et al

BBT-C37 · BBT-C38 · BBT-C39
R84Stress-sensitive neural circuits change the gut microbiome via duodenal glands

Chang H et al

BBT-C37 · BBT-C38
R85Select microbial metabolites in the small intestinal lumen regulate vagal activity via receptor-mediated signaling

Jameson KG et al

BBT-C37 · BBT-C38
R86PIEZO2 in somatosensory neurons controls gastrointestinal transit

Servin-Vences MR et al

BBT-C37 · BBT-C38 · BBT-C39
R87Enteroendocrine cell regulation of the gut-brain axis

Barton JR et al

BBT-C37 · BBT-C38 · BBT-C39
R88Sensory spinal interoceptive pathways and energy balance regulation

Munzberg H, Berthoud HR, Neuhuber W

BBT-C07 · BBT-C37 · BBT-C39
R89Hepatic interoception in health and disease

Berthoud HR et al

BBT-C07 · BBT-C37 · BBT-C39
R90Psychological interventions for interoception in mental health disorders: a systematic review of randomized controlled trials

Heim N et al

BBT-C07 · BBT-C37 · BBT-C39
R91Interoceptive technologies for psychiatric interventions: from diagnosis to clinical applications

Schoeller F et al

BBT-C18 · BBT-C40 · BBT-C41 · BBT-C42 · BBT-C43 · BBT-C48
R92Heart rate variability biofeedback: how and why does it work?

Lehrer PM, Gevirtz R

BBT-C18 · BBT-C41 · BBT-C42 · BBT-C43 · BBT-C48
R93Real-time fMRI neurofeedback boosts heartbeat perception by modulating insula activation during interoceptive attention

Haruki Y et al

BBT-C18 · BBT-C33 · BBT-C41 · BBT-C42 · BBT-C43 · BBT-C44 · BBT-C48
R94Transcutaneous auricular vagus nerve stimulation modulates interoceptive prediction-error processing and allostatic regulation

Ventura-Bort C, Weymar M

BBT-C07 · BBT-C18 · BBT-C33 · BBT-C40 · BBT-C41 · BBT-C42 · BBT-C43 · BBT-C48
R95A systematic review of associations between interoception, vagal tone, and emotional regulation

Pinna T, Edwards DJ

BBT-C18 · BBT-C33 · BBT-C40 · BBT-C41 · BBT-C42 · BBT-C43 · BBT-C48
R96Interoception, contemplative practice, and health

Farb NAS et al

BBT-C33 · BBT-C41 · BBT-C43 · BBT-C48
R97From many to none: meditation and the plasticity of the predictive mind

Laukkonen RE, Slagter HA

BBT-C05 · BBT-C06 · BBT-C09 · BBT-C48
R98Systematic review and meta-analysis of the relationship between heartbeat-evoked potential and interoception

Coll MP et al

BBT-C05 · BBT-C06 · BBT-C09 · BBT-C18 · BBT-C48
R99The respiratory resistance sensitivity task: quantifying respiratory interoception and metacognition

Nikolova N et al

BBT-C05 · BBT-C06 · BBT-C09 · BBT-C18 · BBT-C28 · BBT-C48
R100The heart rate discrimination task: estimating accuracy and precision of interoceptive beliefs

Legrand N et al

BBT-C06 · BBT-C09 · BBT-C18 · BBT-C42 · BBT-C48
0148-claim Evidence Map · CSV0248-claim Evidence Map · JSON03100-publication unified corpus · CSV04100-publication unified corpus · JSON05Canonical package integrity · JSON